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银屑病治疗的成本比较。

Cost comparison of psoriasis treatments.

机构信息

Division of Dermatology, University of Ottawa, Ottawa, ON, Canada.

出版信息

J Cutan Med Surg. 2009 Nov-Dec;13(6):303-7. doi: 10.2310/7750.2009.08088.

DOI:10.2310/7750.2009.08088
PMID:19919807
Abstract

BACKGROUND

Knowledge of the cost of various psoriasis therapeutic options is essential to the prescribing clinician.

OBJECTIVE

To compare the cost of various psoriasis treatments over a 10-year period in the province of Ontario, Canada.

METHODS

We used a hypothetical patient with plaque-type psoriasis of moderate severity with a Psoriasis Area and Severity Index of 10, body surface area of 20%, and no joint involvement. The costs to treat this hypothetical patient with different therapeutic regimens were compared in this study.

RESULTS

In a 60 kg patient, alefacept was the most costly form of therapy, based on two 12-week treatments per year, followed by infliximab 5 mg/kg. In a 90 kg patient, infliximab 5 mg/kg was the most costly, followed by alefacept. The least costly treatment was ultraviolet B phototherapy.

CONCLUSION

With the knowledge of these data, informed prescribing by the dermatologist may reduce the financial burden to the patient, the provincial health care system, and insurance companies.

摘要

背景

了解各种银屑病治疗方案的成本对于处方医生来说至关重要。

目的

比较加拿大安大略省 10 年内各种银屑病治疗方法的成本。

方法

我们使用一位患有斑块状银屑病、病情中度严重、银屑病面积和严重程度指数为 10、体表面积为 20%、无关节受累的假设患者。本研究比较了不同治疗方案治疗该假设患者的成本。

结果

在一位 60 公斤重的患者中,根据每年两次 12 周的治疗,阿法赛普特是最昂贵的治疗方式,其次是英夫利昔单抗 5mg/kg。在一位 90 公斤重的患者中,英夫利昔单抗 5mg/kg 是最昂贵的,其次是阿法赛普特。最便宜的治疗方法是紫外线 B 光疗。

结论

有了这些数据的知识,皮肤科医生的处方可以减轻患者、省级医疗保健系统和保险公司的经济负担。

相似文献

1
Cost comparison of psoriasis treatments.银屑病治疗的成本比较。
J Cutan Med Surg. 2009 Nov-Dec;13(6):303-7. doi: 10.2310/7750.2009.08088.
2
Estimated cost efficacy of systemic treatments that are approved by the US Food and Drug Administration for the treatment of moderate to severe psoriasis.美国食品和药物管理局批准的用于治疗中重度银屑病的系统治疗的成本效益估计。
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Paradoxical effects of cost reduction measures in managed care systems for treatment of severe psoriasis.管理式医疗体系中降低成本措施对重度银屑病治疗的矛盾效应。
Dermatol Online J. 2009 Apr 15;15(4):1.
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Systemic treatment for moderate to severe psoriasis: estimates of failure rates and direct medical costs in a north-eastern US managed care plan.中度至重度银屑病的全身治疗:美国东北部管理式医疗计划中的失败率估计和直接医疗成本
J Dermatolog Treat. 2005 Feb;16(1):37-42. doi: 10.1080/09546630510025941.
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Strategy to manage the treatment of severe psoriasis: considerations of efficacy, safety and cost.重度银屑病治疗管理策略:疗效、安全性及成本考量
Expert Opin Pharmacother. 2003 Sep;4(9):1525-33. doi: 10.1517/14656566.4.9.1525.
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The cost of psoriasis therapies: considerations for therapy selection.
Dermatol Nurs. 2004 Oct;16(5):421-8, 432.
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Would elimination of copayments for phototherapy decrease the cost of treating psoriasis with systemic biologics? A cost analysis.消除光疗的自付费用会降低使用全身性生物制剂治疗银屑病的成本吗?一项成本分析。
Manag Care Interface. 2006 Jun;19(6):39-43.
8
Cost-effectiveness of moderate-to-severe psoriasis treatment.
Expert Opin Pharmacother. 2006 Feb;7(2):157-67. doi: 10.1517/14656566.7.2.157.
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Health economic analyses of psoriasis management: a systematic literature search.银屑病治疗的卫生经济学分析:一项系统文献检索
Arch Dermatol Res. 2016 Nov;308(9):601-616. doi: 10.1007/s00403-016-1673-4. Epub 2016 Jul 19.
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A retrospective cohort study of the impact of biologic therapy initiation on medical resource use and costs in patients with moderate to severe psoriasis.一项回顾性队列研究,旨在评估生物治疗对中重度银屑病患者医疗资源利用和成本的影响。
Br J Dermatol. 2010 Oct;163(4):807-16. doi: 10.1111/j.1365-2133.2010.09944.x.

引用本文的文献

1
Home Narrowband Ultraviolet B Phototherapy for Photoresponsive Skin Conditions: A Health Technology Assessment.家庭窄谱中波紫外线光疗治疗光反应性皮肤疾病:一项卫生技术评估。
Ont Health Technol Assess Ser. 2020 Nov 2;20(12):1-134. eCollection 2020.
2
Ultraviolet Phototherapy Management of Moderate-to-Severe Plaque Psoriasis: An Evidence-Based Analysis.中重度斑块状银屑病的紫外线光疗管理:一项基于证据的分析。
Ont Health Technol Assess Ser. 2009;9(27):1-66. Epub 2009 Nov 1.