40岁以下髋关节骨关节炎患者全髋关节置换术后的异位骨化
Heterotopic ossification in patients with hip osteoarthritis below forty years old after total hip replacement.
作者信息
Koczy Bogdan, Stołtny Tomasz, Swiderski Michał, Pyda Michał, Pajak Jan, Spindel Jerzy, Wawrzynek Wojciech, Miszczyk Leszek, Kasperczyk Sławomir, Widuchowski Jerzy
机构信息
Dr J. Daab Regional Independent Public Hospital of Trauma Surgery, Piekary Slaskie, Poland.
出版信息
Ortop Traumatol Rehabil. 2009 Sep-Oct;11(5):458-66.
BACKGROUND
Even though heterotopic ossification (HO) is most often asymptomatic in patients after total hip replacement (THR), it remains a serious problem in orthopaedics as it is observed in nearly all operated patients.
MATERIALS AND METHODS
The article presents a pre- and post-operative retrospective analysis of heterotopic ossification based on radiographic evidence. The study involved 77 patients below forty years old who underwent THR due to degenerative changes. Heterotopic ossification was evaluated using Brooker's basic four-grade scale.
RESULTS
Heterotopic ossification was diagnosed more often in women. The study confirmed once again that non-steroidal anti-inflammatory drug (NSAID) prophylaxis reduces the risk of ossification. We propose that the hydroxyapatite coating of implants may also contribute to a higher incidence of heterotopic ossification in operated patients.
CONCLUSIONS
A history of surgical procedures and a lack of NSAID prophylaxis contributed to heterotopic ossification in the region of the replaced hip joint in the study group.
背景
尽管异位骨化（HO）在全髋关节置换术（THR）后的患者中大多无症状，但在几乎所有接受手术的患者中均有观察到，它仍然是骨科领域的一个严重问题。
材料与方法
本文基于影像学证据对异位骨化进行了术前和术后的回顾性分析。该研究纳入了77例因退行性变接受THR的40岁以下患者。使用布鲁克（Brooker）基本四级量表评估异位骨化情况。
结果
女性中异位骨化的诊断更为常见。该研究再次证实非甾体抗炎药（NSAID）预防可降低骨化风险。我们认为植入物的羟基磷灰石涂层也可能导致手术患者异位骨化发生率较高。
结论
手术史和缺乏NSAID预防是研究组中置换髋关节区域发生异位骨化的原因。
Zotero 插件