Glaucoma Service at the Department of Ophthalmology at the Medical University of South Carolina, Charleston, South Carolina, U.S.A.
J Glaucoma. 1995 Jun;4(3):164-9.
We evaluated the results of 17 consecutive patients with high intraocular pressures and visually significant cataracts who underwent combined phacoemulsification and trabeculectomy.
We individually matched each patient by age, race, and intraocular pressure (trabeculectomy group only) to two control groups: group 1, patients who had combined phacoemulsification and trabeculectomy and whose intraocular pressures were controlled preoperatively (pressure </=18 mm Hg), and group 2, patients who had high intraocular pressures preoperatively and trabeculectomy alone. Only patients with chronic open-angle glaucoma undergoing initial filtration surgery were included.
One year postsurgery there was no statistically significant difference between study patients and either control group in terms of intraocular pressure (p > 0.05). Moreover, no statistical difference was observed between groups at 1 year postsurgery in number of glaucoma medications, bleb height or extent, anterior chamber depth, or bleb vascularity (p > 0.05). Additionally, both study and control patients had a statistically similar peak pressure the first month following surgery (p > 0.05). Complications were similar among groups.
This study suggests that patients with chronic open-angle glaucoma and high intraocular pressure may undergo combined trabeculectomy and phacoemulsification and achieve long-term postoperative intraocular control similar to those patients who have trabeculectomy only or a combined procedure and controlled preoperative pressure.
我们评估了 17 例高眼压和明显视觉白内障患者联合施行超声乳化白内障吸除术和小梁切除术的结果。
我们通过年龄、种族和眼压（仅在小梁切除术组）将每个患者与两组对照患者进行单独匹配：对照组 1 为联合施行超声乳化白内障吸除术和小梁切除术且术前眼压得到控制（眼压 <= 18mmHg）的患者，对照组 2 为术前眼压高且单独施行小梁切除术的患者。仅包括慢性开角型青光眼初次滤过性手术的患者。
术后 1 年，研究患者与任何一组对照患者在眼压方面均无统计学显著差异（p > 0.05）。此外，术后 1 年各组之间在青光眼药物使用数量、滤过泡高度或范围、前房深度或滤过泡血管化方面无统计学差异（p > 0.05）。另外，研究患者和对照患者在术后第 1 个月的眼压峰值也具有统计学相似性（p > 0.05）。各组之间的并发症相似。
本研究提示慢性开角型青光眼和高眼压患者可联合施行小梁切除术和超声乳化白内障吸除术，并且术后眼压控制与仅施行小梁切除术或施行联合手术且术前眼压得到控制的患者相似。
