Department of Surgery, Columbia University Medical Center, Vanderbilt Clinic 1010, 622 W 168th Street, New York, NY 10032, USA.
World J Surg. 2010 Apr;34(4):669-74. doi: 10.1007/s00268-009-0268-z.
BACKGROUND The history of measuring myocardial edema by two-dimensional echocardiography and the pathophysiology of myocardial edema are reviewed. METHODS The relevance of this subject to management of children undergoing corrective surgery for single ventricle physiology and tetralogy of Fallot is reviewed. RESULTS Evidence is presented that myocardial edema is an ongoing clinical problem with relevance to management and outcomes. Methods for measuring mass increases noninvasively in the range of 10-25% with increases in myocardial water content on the order of 2-4% are now well established. CONCLUSIONS These methods and advanced animal models replicating conditions of surgery for cyanotic congenital heart disease set the stage for clinical advances in this important area.
本文回顾了二维超声心动图测量心肌水肿的历史和心肌水肿的病理生理学。
本文回顾了这一主题与行单心室生理矫正术和法洛四联症患儿管理的相关性。
有证据表明，心肌水肿是一个持续存在的临床问题，与管理和结果有关。目前已经建立了测量心肌质量在 10-25%范围内增加的非侵入性方法，心肌含水量增加约 2-4%。
这些方法和模拟紫绀性先天性心脏病手术条件的先进动物模型为该重要领域的临床进展奠定了基础。
