Obeid Karam M, Effendi Abdul R, Khatib Riad
Division of Infectious Diseases, Department of Internal Medicine, St. John Hospital and Medical Center, Detroit, Michigan 48236, USA.
Scand J Infect Dis. 2009;41(11-12):890-2. doi: 10.3109/00365540903214306.
We present the case of an immunocompetent host with acute glomerulonephritis following parvovirus B19 infection. Renal biopsy demonstrated immune-mediated disease; parvovirus B19 DNA was detected in renal tissue and blood. The patient improved with corticosteroid therapy. Repeat serology 3 months later confirmed recovery from the acute viral infection, although viraemia persisted.
我们报告了一例免疫功能正常的宿主在感染细小病毒B19后发生急性肾小球肾炎的病例。肾活检显示为免疫介导性疾病;在肾组织和血液中检测到细小病毒B19 DNA。患者经皮质类固醇治疗后病情好转。3个月后复查血清学检查证实已从急性病毒感染中恢复,尽管病毒血症仍持续存在。