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阻塞性睡眠呼吸暂停综合征患者睡眠期间上气道的动态变化

Dynamic upper airway changes during sleep in patients with obstructive sleep apnea syndrome.

作者信息

Chuang Li-Pang, Chen Ning-Hung, Li Hsueh-Yu, Lin Shih-Wei, Chou Yu-Ting, Wang Chao-Jan, Liao Yu-Fang, Tsai Ying-Huang

机构信息

Sleep Center, Chang Gung University, Taipei, Taiwan.

出版信息

Acta Otolaryngol. 2009 Dec;129(12):1474-9. doi: 10.3109/00016480902780242.

DOI:10.3109/00016480902780242
PMID:19922100
Abstract

CONCLUSION

The narrowing pattern of the upper airway in obstructive sleep apnea patients may be different in sleep as compared with awake. Three different types of obstruction were observed in these subjects during drug-induced sleep. The different obstruction pattern during drug-induced sleep suggests that different strategies should be selected in upper airway management.

OBJECTIVES

To identify the sites of narrowing and evaluate dynamic upper airway movement in patients with obstructive sleep apnea syndrome (OSAS) while awake and asleep.

PATIENTS AND METHODS

This study included 10 patients treated for OSAS between August 2003 and June 2004. Overnight polysomnography was performed on all patients. Parameters including gender, age, neck circumference, and body mass index were recorded. Ultra-fast MRI during awake and drug-induced sleep was arranged to evaluate the dynamic motion of the upper airway.

RESULTS

The narrowing pattern of the upper airway during awake differed from the narrowing pattern during drug-induced sleep in 3 of 10 subjects. Three different types, palatal obstruction, combined upper and lower pharyngeal obstruction, and circumferential obstruction of the upper airway, were observed in these patients during drug-induced sleep.

摘要

结论

阻塞性睡眠呼吸暂停患者上气道的狭窄模式在睡眠时可能与清醒时不同。在这些受试者药物诱导睡眠期间观察到三种不同类型的阻塞。药物诱导睡眠期间不同的阻塞模式表明在上气道管理中应选择不同的策略。

目的

确定阻塞性睡眠呼吸暂停综合征(OSAS)患者清醒和睡眠时上气道狭窄部位并评估上气道的动态运动。

患者与方法

本研究纳入了2003年8月至2004年6月期间接受OSAS治疗的10例患者。对所有患者进行整夜多导睡眠监测。记录性别、年龄、颈围和体重指数等参数。安排清醒和药物诱导睡眠期间的超快磁共振成像以评估上气道的动态运动。

结果

10名受试者中有3名清醒时上气道狭窄模式与药物诱导睡眠时不同。在这些患者药物诱导睡眠期间观察到三种不同类型,即腭部阻塞、上、下咽联合阻塞和上气道环形阻塞。

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