简报：捷克本地山羊品种中酪蛋白簇基因的多态性。

Short communication: Polymorphism of casein cluster genes in Czech local goat breeds.

机构信息

Institute of Animal Science, 104 00 Prague, Czech Republic.

出版信息

J Dairy Sci. 2009 Dec;92(12):6197-201. doi: 10.3168/jds.2008-1519.

DOI:10.3168/jds.2008-1519

PMID:19923624

Abstract

The 4 casein loci were evaluated as haplotypes in 2 dairy goat breeds kept in the Czech Republic. Analysis of 41 White Shorthaired (WSH) trio families and 44 Brown Shorthaired (BSH) trio families revealed 14 and 20 haplotypes, respectively. Various genomic techniques were used to type the casein loci. Twenty-two different combinations of these alleles (casein haplotypes, in the order CSN1S1-CSN2-CSN1S2-CSN3) were found. Only 5 haplotypes in the WSH breed and 6 haplotypes in the BSH breed occurred at frequencies >0.05. For the WSH breed, the most common haplotype was FCFB (0.260), whereas for the BSH breed, the most common haplotype was FCFA (0.217). The information on the haplotype variability in both breeds could be used in breeding programs aimed at preserving biodiversity or selecting animals for specific protein production and cheesemaking.

摘要

在捷克共和国饲养的 2 个奶山羊品种中，对 4 个酪蛋白基因座进行了单倍型评估。对 41 个白色短毛（WSH）三大家系和 44 个棕色短毛（BSH）三大家系的分析分别揭示了 14 个和 20 个单倍型。使用各种基因组技术对酪蛋白基因座进行了分型。发现了 22 种不同的等位基因（酪蛋白单倍型，CSN1S1-CSN2-CSN1S2-CSN3 顺序）组合。在 WSH 品种中，只有 5 种单倍型和 BSH 品种中的 6 种单倍型的频率>0.05。对于 WSH 品种，最常见的单倍型是 FCFB（0.260），而对于 BSH 品种，最常见的单倍型是 FCFA（0.217）。这两个品种的单倍型变异性信息可用于保护生物多样性或选择特定蛋白质生产和制奶酪的动物的育种计划。