Kawada Tomoyuki, Kuratomi Yushiro, Kanai Tomoe, Suto Sachiko, Nishime Akemi, Koizumi Miyuki, Nakano Noriko
Department of Hygiene and Public Health, Nippon Medical School, Japan.
Work. 2009;34(1):89-94. doi: 10.3233/WOR-2009-0905.
Although the prevalence of obesity in the Japanese adult population is lower than that in the US adult population, there appears to be a trend towards increase in the prevalence of obesity in Japanese men. In this study, the usefulness of waist circumference (WC) and body mass index (BMI) determination as predictors of metabolic syndrome (MetS) was evaluated in Japanese working men.
A cross-sectional study was conducted in the spring of 2007. The sample included 3,486 working men aged 35 to 59 years. The standard criteria of the International Diabetes Federation were used to determine the prevalence of MetS. The results were adjusted for age, smoking, habitual drinking and serum uric acid. To calculate the OR, MetS was tentatively defined as the presence of two or more of the following criteria in the subjects: high blood pressure, glucose intolerance, and dyslipidemia.
The prevalence of MetS was 17.0%, and it increased with age until the mid-50s. The percentages of subjects with high blood pressure, glucose intolerance, dyslipidemia and hyperuricemia were 57.3, 12.7, 29.4 and 21.3%, respectively. As compared to that in the subjects classified in the lowest WC quintile, the ORs (95% confidence interval (CI)) for MetS of a WC in the range of 76.0 to 81.4, 81.5 to 85.9, 86.0 to 90.9, and >or= 91 cm were 1.66 (1.13-2.45), 1.74 (1.13-2.67), 2.37 (1.50-3.74), and 2.84(1.73-4.64), respectively. In contrast, the OR (95% CI) for MetS of a BMI in the range of 24.5 to 26.5 and >or= 26.6 Kg/m2 were 2.43 (1.58-3.73) and 3.27 (2.04-5.27), which just about reached the significance level.
The risk of MetS was correlated with the obesity indices. However, BMI values in the high normal range were not significantly associated with the risk of MetS.
尽管日本成年人群体中的肥胖患病率低于美国成年人群体，但日本男性的肥胖患病率似乎呈上升趋势。在本研究中，对日本在职男性中腰围（WC）和体重指数（BMI）测定作为代谢综合征（MetS）预测指标的实用性进行了评估。
于2007年春季开展了一项横断面研究。样本包括3486名年龄在35至59岁的在职男性。采用国际糖尿病联盟的标准标准来确定MetS的患病率。结果针对年龄、吸烟、习惯性饮酒和血清尿酸进行了校正。为计算比值比（OR），MetS被初步定义为受试者中存在以下两种或更多标准：高血压、葡萄糖耐量异常和血脂异常。
MetS的患病率为17.0%，且在50岁中期之前随年龄增加而上升。高血压、葡萄糖耐量异常、血脂异常和高尿酸血症受试者的百分比分别为57.3%、12.7%、29.4%和21.3%。与WC处于最低五分位数组的受试者相比，WC在76.0至81.4、81.5至85.9、86.0至90.9以及≥91厘米范围内时，MetS的OR（95%置信区间（CI））分别为1.66（1.13 - 2.45）、1.74（1.13 - 2.67）、2.37（1.50 - 3.74）以及2.84（1.73 - 4.64）。相比之下，BMI在24.5至26.5以及≥26.6 Kg/m²范围内时，MetS的OR（95% CI）分别为2.43（1.58 - 3.73）和3.27（2.04 - 5.27），几乎达到显著水平。
MetS的风险与肥胖指标相关。然而，高正常范围的BMI值与MetS的风险无显著关联。
