Biomedical Imaging Division, VT-WFU School of Biomedical Engineering and Sciences, Virginia Tech, Blacksburg, VA, USA.
J Xray Sci Technol. 2009;17(4):295-303. doi: 10.3233/XST-2009-0230.
In the computed tomography (CT) field, one recent invention is the so-called carbon nanotube (CNT) based field emission x-ray technology. On the other hand, compressive sampling (CS) based interior tomography is a new innovation. Combining the strengths of these two novel subjects, we apply the interior tomography technique to local mouse cardiac imaging using respiration and cardiac gating with a CNT based micro-CT scanner. The major features of our method are: (1) it does not need exact prior knowledge inside an ROI; and (2) two orthogonal scout projections are employed to regularize the reconstruction. Both numerical simulations and in vivo mouse studies are performed to demonstrate the feasibility of our methodology.
在计算机断层扫描(CT)领域,最近的一项发明是所谓的基于碳纳米管(CNT)的场发射 X 射线技术。另一方面,基于压缩采样(CS)的内部层析成像则是一项新的创新。我们将这两个新课题的优势结合起来,在基于 CNT 的微 CT 扫描仪上使用呼吸和心脏门控进行局部小鼠心脏成像,应用内部层析成像技术。我们方法的主要特点是:(1)它不需要 ROI 内的精确先验知识;(2)采用两个正交的扫描投影来正则化重建。进行了数值模拟和体内小鼠研究,以证明我们方法的可行性。