Benson Aaron G, Djalilian Hamid R
Department of Otolaryngology-Head and Neck Surgery, University of Illinois at Chicago, Chicago, IL, USA.
Ear Nose Throat J. 2009 Nov;88(11):E1-4.
Hydroxyapatite bone cement is a versatile material used to reconstruct many types of bony surgical defects, and its applications have been widely reported in the literature. Still, complications of its use do occur. We describe 2 cases of hydroxyapatite resorption and subsequent seroma formation in patients who had undergone retrosigmoid craniotomy. The presentation in both cases mimicked a CSF leak. In both cases, the fragmented cement was removed, and the patient experienced no further complications. While hydroxyapatite cement is a highly useful product for the reconstruction of some craniofacial or skull base defects, we believe that it should not be used for the reconstruction of retrosigmoid/suboccipital craniotomies because it is associated with unacceptably high complication rates. Surgeons must exercise caution in selecting candidates for hydroxyapatite reconstruction of cranial defects.
羟基磷灰石骨水泥是一种用于修复多种类型骨手术缺损的多功能材料，其应用在文献中已有广泛报道。然而，使用它确实会出现并发症。我们描述了2例在乙状窦后开颅术后发生羟基磷灰石吸收及随后血清肿形成的病例。两例病例的表现都类似脑脊液漏。在这两例病例中，均取出了破碎的骨水泥，患者未再出现进一步并发症。虽然羟基磷灰石骨水泥对于修复一些颅面或颅底缺损是一种非常有用的产品，但我们认为它不应被用于乙状窦后/枕下开颅术的修复，因为它会导致高得难以接受的并发症发生率。外科医生在选择进行颅骨缺损羟基磷灰石修复的患者时必须谨慎。
