Department of Ultrasound, Chinese PLA General Hospital, Beijing, China.
Int J Hyperthermia. 2009;25(6):455-61. doi: 10.1080/02656730903066608.
To evaluate the feasibility, safety and therapeutic effects of ultrasound (US)-guided percutaneous microwave (MW) ablation in the treatment of adrenal metastasis.
From May 2006 to April 2008, five consecutive patients with pathologically proven unilateral adrenal metastases with a diameter of 2.3 to 4.5 cm were treated by US-guided percutaneous MW ablation. Four metastases were in the right side, one metastasis was in the left side. For each application, two cooled-shaft needle antennae were percutaneously inserted into the tumour under real-time US guidance. One thermocouple needle was inserted at the periphery of the tumour to monitor temperature in real-time during MW ablation. MW emission was ended when the entire tumour became hyperechoic and the temperature at the tumour border reached 54 degrees C for at least 3 min. Technical success was defined as loss of tumour enhancement on contrast-enhanced imagings.
All adrenal metastases were completely ablated after scheduled MW ablation sessions (mean, 1.2 sessions, range, 1 to 2 sessions). No major complications related to MW ablation occurred. In a median follow-up of 19 months (range 8 to 31 months), persistent absence of tumour enhancement was observed in the treated tumour in all patients.
US-guided percutaneous MW ablation appears to be a safe and effective therapy in selected adrenal metastasis.
评估超声引导经皮微波（MW）消融治疗肾上腺转移瘤的可行性、安全性和疗效。
2006 年 5 月至 2008 年 4 月，连续 5 例经病理证实的单侧肾上腺转移瘤患者，直径 2.3 至 4.5cm，接受超声引导经皮 MW 消融治疗。4 例转移瘤位于右侧，1 例位于左侧。对于每个应用，将两根冷轴针天线在实时超声引导下经皮插入肿瘤内。在 MW 消融过程中，在肿瘤边缘插入一根热电偶针以实时监测温度。当整个肿瘤呈高回声且肿瘤边界温度达到 54°C 至少 3 分钟时，MW 发射结束。技术成功定义为肿瘤增强在对比增强成像上的丧失。
所有肾上腺转移瘤均在预定的 MW 消融疗程后完全消融（平均 1.2 个疗程，范围 1 至 2 个疗程）。MW 消融无严重相关并发症。在中位随访 19 个月（范围 8 至 31 个月）期间，所有患者治疗肿瘤的肿瘤增强均持续消失。
超声引导经皮 MW 消融术对选定的肾上腺转移瘤似乎是一种安全有效的治疗方法。
