Department of Experimental Medicine, Virology Section, Sapienza University of Rome, Rome, Italy.
Clin Microbiol Infect. 2010 Apr;16(4):391-3. doi: 10.1111/j.1469-0691.2009.03119.x. Epub 2009 Nov 19.
To investigate the burden of influenza-like illness (ILI), patients attending an emergency department during the influenza season were tested for several common respiratory viruses, using PCR-based methods. Influenza A viruses were detected in 25 of 103 recruited patients (24%), rhinoviruses in 15%, and respiratory syncytial virus in only one. The data suggest that triage criteria based on ILI case definitions would not contain the spread of the influenza virus during pandemic alerts and could lead to unnecessary isolation of patients with other infections. Application of broader triage criteria followed by timely molecular diagnosis could be effective in preventing new respiratory agent transmission.
为了调查流感样疾病(ILI)的负担,在流感季节,研究人员使用基于 PCR 的方法对急诊科就诊的患者进行了多种常见呼吸道病毒的检测。在 103 名招募的患者中,有 25 名(24%)检测到甲型流感病毒,15 名检测到鼻病毒,只有 1 名检测到呼吸道合胞病毒。数据表明,基于 ILI 病例定义的分诊标准无法控制流感大流行期间流感病毒的传播,并且可能导致对其他感染患者的不必要隔离。应用更广泛的分诊标准,然后及时进行分子诊断,可能有助于预防新的呼吸道病原体传播。