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[一例原发性睾丸恶性淋巴瘤九年间隔后对侧睾丸复发的病例报告]

[A case of primary testicular malignant lymphoma associated with contralateral testicular recurrence after a nine-year interval: a case report].

作者信息

Maruyama Takuo, Hashimoto Takahiko, Suzuki Toru, Ueda Yasuo, Higuchi Yoshihide, Qui Jun, Kondou Nobuyuki, Nojima Michio, Yamamoto Shingo, Shima Hiroki, Hirota Seiichi, Okada Masaya

机构信息

The Department of Urology, Hyogo College of Medicine.

出版信息

Hinyokika Kiyo. 2009 Oct;55(10):639-43.

Abstract

A 69-year-old man visited our hospital in February 1996 with a chief complain of left scrotal swelling. The left scrotal content was hard by palpation and ultrasonography showed a hypo-echoic lesion. Left high orchiectomy was performed with suspicion of a testicular tumor. Pathological examination demonstrated a diffuse large B-cell lymphoma (DLBCL) originating from the left testis, and then he underwent 5 courses of chemotherapy consisting of THP-COP (THP-adriamycin, cyclophosphamide, vincristin, predonisone). Following the treatment for five years, he had no evidence of recurrence. Nine years later, in October 2005, he noticed right scrotal swelling. He underwent right high orchiectmy with suspicion of a contralateral testicular malignant lymphoma. Pathological examination revealed DLBCL. He underwent chemotherapy (rituximab-THP-COP) and achieved complete remission again. He is doing well without recurrence of disease for three years after the last treatment.

摘要

一名69岁男性于1996年2月因左侧阴囊肿胀为主诉前来我院就诊。触诊时左侧阴囊内容物质地坚硬,超声检查显示为低回声病变。因怀疑睾丸肿瘤行左侧高位睾丸切除术。病理检查显示为起源于左侧睾丸的弥漫性大B细胞淋巴瘤(DLBCL),随后他接受了5个疗程的THP-COP(吡柔比星、环磷酰胺、长春新碱、泼尼松)化疗。治疗五年后,无复发迹象。九年后,即2005年10月,他发现右侧阴囊肿胀。因怀疑对侧睾丸恶性淋巴瘤行右侧高位睾丸切除术。病理检查显示为DLBCL。他接受了化疗(利妥昔单抗-THP-COP)并再次实现完全缓解。上次治疗后三年来他情况良好,无疾病复发。

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