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一例滥用麦角酸二乙酰胺(LSD)后出现持续面部视幻觉的病例:一项功能磁共振成像研究

A case of persistent visual hallucinations of faces following LSD abuse: a functional Magnetic Resonance Imaging study.

作者信息

Iaria Giuseppe, Fox Christopher J, Scheel Michael, Stowe Robert M, Barton Jason J S

机构信息

Department of Psychology, University of Calgary, Calgary, Alberta, Canada.

出版信息

Neurocase. 2010 Apr;16(2):106-18. doi: 10.1080/13554790903329141. Epub 2009 Nov 18.

DOI:10.1080/13554790903329141
PMID:19927262
Abstract

In this study, we report the case of a patient experiencing hallucinations of faces that could be reliably precipitated by looking at trees. Using functional Magnetic Resonance Imaging (fMRI), we found that face hallucinations were associated with increased and decreased neural activity in a number of cortical regions. Within the same fusiform face area, however, we found significant decreased and increased neural activity according to whether the patient was experiencing hallucinations or veridical perception of faces, respectively. These findings may indicate key differences in how hallucinatory and veridical perceptions lead to the same phenomenological experience of seeing faces.

摘要

在本研究中,我们报告了一例患者的病例,该患者会出现面部幻觉,而看树能够可靠地诱发这种幻觉。通过功能磁共振成像(fMRI),我们发现面部幻觉与多个皮质区域神经活动的增加和减少有关。然而,在同一个梭状面孔区,我们发现根据患者是正在经历面部幻觉还是对面部有真实感知,神经活动分别显著减少和增加。这些发现可能表明,幻觉性感知和真实感知导致相同的看到面孔的现象学体验的方式存在关键差异。

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