[炎症性肠病中的血栓形成：机制与危险因素]
[Thrombosis in inflammatory bowel disease: mechanisms and risk factors].
作者信息
Mouelhi Leila, Mekki Haïfa, Debbeche Radhouane, Salem Mohamed, Najjar Taoufik
机构信息
Service de Gastroentérologie. Hôpital Charles Nicolle, Tunis.
出版信息
Tunis Med. 2009 May;87(5):307-10.
BACKGROUND
Thromboembolic manifestations are frequent in patients with inflammatory bowel disease.
AIMS
To explaim the mechanisms of thromboembolic manifestations in inflammatory bowel disease.
METHODS
Literature review.
RESULTS
Risk factors of thrombosis in inflammatory bowel disease are acquired or genetic. The most important factors are thrombocytosis, increased of activation of platelets and hyperhomocysteinemia. Other factors such factor V leiden, antithrombin III and antiphospholipid antibodies are observed in inflammatory bowel disease patients but not always correlated with thromboembolic manifestations.
CONCLUSION
The mechanisms of thrombosis in inflammatory bowel disease are complex are intricate.
背景
血栓栓塞表现在炎症性肠病患者中很常见。
目的
解释炎症性肠病中血栓栓塞表现的机制。
方法
文献综述。
结果
炎症性肠病中血栓形成的危险因素是后天获得的或遗传的。最重要的因素是血小板增多、血小板活化增加和高同型半胱氨酸血症。在炎症性肠病患者中还观察到其他因素，如因子V Leiden、抗凝血酶III和抗磷脂抗体，但并不总是与血栓栓塞表现相关。
结论
炎症性肠病中血栓形成的机制复杂且错综复杂。
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