Max-Plank Institute of Microstructure Physics, Halle D-06120, Germany.
Langmuir. 2009 Dec 1;25(23):13284-9. doi: 10.1021/la903106j.
An emerging nanofabrication technology is to synthesize nanoscale inorganic materials with narrow size distribution using biological systems, which are size-constrained, fairly robust, and easily removable. Apoferritin, a spherical and hollow protein complex, was subjected to atomic layer deposition of TiO(2). The growth of TiO(2) on the protein surface was investigated as a function of the precursor exposure and purge length. Thermal pretreatment and osmotic dehydration lead to controllable deposition both on the outer surface and within the inner cavity of apoferritin. Depending on the experimental conditions, either hollow spherical nanoparticles or core-shell nanoparticles comprising TiO(2) were identified.
一种新兴的纳米制造技术是利用生物系统合成具有窄尺寸分布的纳米级无机材料，这些生物系统具有尺寸限制、相当坚固和易于去除的特点。脱铁蛋白是一种球形和中空的蛋白质复合物，它可以进行原子层沉积 TiO(2)。研究了 TiO(2)在蛋白质表面的生长情况，作为前体暴露和吹扫长度的函数。热预处理和渗透脱水导致脱铁蛋白的外表面和内腔内部都可以进行可控沉积。根据实验条件，可以得到空心球形纳米颗粒或包含 TiO(2)的核壳纳米颗粒。
