Department of Health Sciences, University of Jyväskylä, Jyväskylä, Finland.
J Bone Miner Res. 2010 May;25(5):1034-41. doi: 10.1359/jbmr.091115.
The purpose of this 7-year prospective longitudinal study was to examine whether the level and consistency of leisure-time physical activity (LTPA) during adolescence affected the bone mineral content (BMC) and bone mineral density (BMD) attained at early adulthood. The study subjects were 202 Finnish girls who were 10 to 13 years of age at baseline. Bone area (BA), BMC, and BMD of the total body (TB), total femur (TF), and lumbar spine (L(2)-L(4)) were assessed by dual-energy X-ray absorptiometry (DXA). Scores of LTPA were obtained by questionnaire. Girls were divided into four groups: consistently low physical activity (G(LL)), consistently high (G(HH)), and changed from low to high (G(LH)) and from high to low (G(HL)) during 7 years of follow-up. At baseline, no differences were found in BA, BMC, and BMD among the groups in any of the bone sites. Compared with the G(LL) group, the G(HH) group had higher BMC (11.7% in the TF, p < .05) and BMD at the TB (4.5%) and the TF (12.2%, all p < .05) at age 18. Those in the G(LH) group also had higher a BMC at each site (8.5% to 9.4%, p < .05) and a higher BMD in the TB (5.4%) and the TF (8.9%) than that of G(LL) (all p < 0.05) at the age 18. Our results suggest that long-term leisure-time physical activity has a positive effect on bone mass gain of multiple bone sites in girls during the transition from prepuberty to early adulthood. In addition, girls whose physical activity increases during adolescence also benefit from bone mass gain.
本为期 7 年的前瞻性纵向研究旨在探讨青少年时期休闲时间体力活动（LTPA）的水平和一致性是否会影响成年早期获得的骨矿物质含量（BMC）和骨矿物质密度（BMD）。研究对象为 202 名芬兰女孩，基线时年龄为 10 至 13 岁。通过双能 X 射线吸收法（DXA）评估全身（TB）、总股骨（TF）和腰椎（L2-L4）的骨面积（BA）、BMC 和 BMD。通过问卷获得 LTPA 评分。女孩被分为四组：长期低体力活动（G(LL)）、长期高体力活动（G(HH)）、7 年随访期间从低到高（G(LH)）和从高到低（G(HL)）的体力活动变化。在基线时，各组在任何骨部位的 BA、BMC 和 BMD 均无差异。与 G(LL)组相比，G(HH)组在 TF 处的 BMC 更高（11.7%，p<.05），TB 和 TF 处的 BMD 更高（分别为 4.5%和 12.2%，均 p<.05）。G(LH)组在每个部位的 BMC 也更高（8.5%至 9.4%，p<.05），TB 和 TF 的 BMD 更高（分别为 5.4%和 8.9%，均 p<.05）。我们的结果表明，长期休闲时间体力活动对女孩从青春期前到成年早期过渡期间多个骨部位的骨量增加具有积极影响。此外，青少年时期体力活动增加的女孩也受益于骨量增加。
