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丙烯酸眼假体急性过敏反应的特征与处理

Features and management of an acute allergic response to acrylic ocular prostheses.

作者信息

Patel Vikesh, Allen David, Morley Ana M S, Malhotra Raman

机构信息

CorneoPlastic Unit, Queen Victoria Hospital, East Grinstead, UK.

出版信息

Orbit. 2009;28(6):339-41. doi: 10.3109/01676830903104660.

Abstract

PURPOSE

To report the occurrence, causes and treatment of an acute allergic response to the acrylic resin used in ocular prostheses.

METHODS

Retrospective review of presenting history, clinical findings and treatment of two cases.

RESULTS

Both patients developed an acute onset hypersensitivity reaction thought to be due to the acrylic resin found in the ocular prosthesis. The first patient was successfully switched to a glass eye. The prosthesis of the second patient was treated with an extra long curing cycle, after which, the patient was able to tolerate their prosthesis with no complications.

CONCLUSION

The residual unpolymerized monomer that is present within poly-methylmethacrylate (PMMA) can rarely cause an allergic reaction. As an alternative to a glass eye the prosthesis may be subjected to an extended curing cycle converting more of the monomer to polymer.

摘要

目的

报告眼部假体中使用的丙烯酸树脂引起的急性过敏反应的发生情况、原因及治疗方法。

方法

对两例病例的就诊史、临床发现及治疗进行回顾性分析。

结果

两名患者均出现急性超敏反应,认为是由眼部假体中的丙烯酸树脂所致。第一名患者成功更换为义眼。第二名患者的假体采用超长固化周期进行处理,之后患者能够耐受假体且无并发症。

结论

聚甲基丙烯酸甲酯(PMMA)中存在的残留未聚合单体极少会引起过敏反应。作为义眼的替代方案,可对假体进行延长固化周期处理,使更多单体转化为聚合物。

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