Carabello Blase A
Veterans Affairs Medical Center, Medical Service (111), 2002 Holcombe Boulevard, Houston, TX 77030, USA.
Curr Treat Options Cardiovasc Med. 2009 Dec;11(6):419-25. doi: 10.1007/s11936-009-0044-2.
Because there is no proven effective medical therapy for mitral regurgitation (MR), mitral valve repair (MVRpr) is the treatment of choice for patients with severe primary nonrheumatic MR. A successfully performed and properly timed MVRpr may lead to a normal lifestyle and life span. The alternative to repair is mitral valve replacement. Although there have been no randomized trials of repair versus replacement, almost all reported series demonstrate superior outcomes with repair, and current guidelines clearly prefer MVRpr over mitral valve replacement for patients with nonrheumatic MR.
由于目前尚无经证实有效的二尖瓣反流（MR）药物治疗方法，二尖瓣修复术（MVRpr）是重度原发性非风湿性MR患者的首选治疗方式。成功实施且时机恰当的MVRpr可使患者拥有正常的生活方式和寿命。修复的替代方案是二尖瓣置换术。尽管尚无关于修复术与置换术的随机对照试验，但几乎所有报道的系列研究均表明修复术的效果更佳，并且当前指南明确建议，对于非风湿性MR患者，MVRpr优于二尖瓣置换术。
