2001 年 8 月至 2004 年 4 月，在印度尼西亚爪哇岛开展轮状病毒监测，以确定疾病负担和流行病学情况。

Rotavirus surveillance to determine disease burden and epidemiology in Java, Indonesia, August 2001 through April 2004.

机构信息

Community Health and Nutrition Research Laboratories (CHN-RL), Purworejo Member of INDEPTH Site and Department of Public Health, Center of Reproductive Health, Faculty of Medicine, Gadjah Mada University, Bulaksumur, Yogyakarta, Indonesia.

出版信息

Vaccine. 2009 Nov 20;27 Suppl 5:F61-6. doi: 10.1016/j.vaccine.2009.09.004.

DOI:10.1016/j.vaccine.2009.09.004

PMID:19931722

Abstract

This study estimates rotavirus disease burden in children under age 3 years presenting with acute gastroenteritis to hospitals in Purworejo district and Yogyakarta city from August 2001 to April 2004. Among a total of 8929 hospitalized children, 1397 (16%) presented with acute gastroenteritis and of the 1321 stool samples tested, 705 (53%) were positive for rotavirus. Rotavirus infections were most common among children aged 7-23 months and rotavirus was more common during the dry season (June through August). Logistic regression analysis showed no differences in socioeconomic indicators between the rotavirus positive and negative admissions. Rotavirus vaccination may prevent a large proportion of all hospitalizations of young children under 3 years of age presenting with acute gastroenteritis.

摘要

本研究估计了 2001 年 8 月至 2004 年 4 月期间，在普罗沃罗佐地区和日惹市因急性肠胃炎住院的 3 岁以下儿童的轮状病毒疾病负担。在总共 8929 名住院儿童中，有 1397 名（16%）出现急性肠胃炎，在 1321 份粪便样本中，有 705 份（53%）轮状病毒检测呈阳性。7-23 月龄儿童中轮状病毒感染最为常见，且轮状病毒在旱季（6 月至 8 月）更为常见。逻辑回归分析显示，轮状病毒阳性和阴性入院病例的社会经济指标无差异。轮状病毒疫苗接种可能预防很大一部分 3 岁以下因急性肠胃炎住院的幼儿。