Division of Pediatric Rheumatology, Texas Children's Hospital/Baylor College of Medicine, 6621 Fannin Street MC 3-2290, Houston, TX 77030, USA.
Neurol Clin. 2010 Feb;28(1):61-73. doi: 10.1016/j.ncl.2009.09.004.
Among the collagen vascular diseases neurologic manifestations have been most commonly recognized and well-studied in systemic lupus erythematosus (SLE, lupus). Neurologic manifestations are less prevalent in other systemic inflammatory and autoimmune disorders. This review focuses on the clinical presentation, pathophysiology, and treatment strategies of neuropsychiatric lupus (NPSLE) in children and adults.
在胶原血管疾病中,神经系统表现最常被认识和研究,系统性红斑狼疮(SLE,狼疮)就是其中之一。在其他系统性炎症性和自身免疫性疾病中,神经系统表现则较为少见。本文重点介绍儿童和成人神经精神性狼疮(NPSLE)的临床表现、病理生理学和治疗策略。