Maeda Taketoshi, Tanoue Yoshihisa, Nakashima Atsuhiro, Tominaga Ryuji
Department of Cardiovascular Surgery, Kyushu University Heart Center, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Interact Cardiovasc Thorac Surg. 2010 Feb;10(2):350-1. doi: 10.1510/icvts.2009.220582. Epub 2009 Nov 20.
Prolonged support with left ventricular assist system (LVAS) increases the risk of device-related infection. We experienced a rare complication of LVAS: an infectious aneurysm at the apical cannula, which appeared with atypical presentation. A 27-year-old male, who developed acute aggravation of dilated cardiomyopathy, was placed on extra-corporeal type LVAS. Six months later, the patient suffered from methicillin-resistant Staphylococcus aureus (MRSA) sepsis that lasted for as long as three months despite intensive antibiotic therapy. At 17 months after the implantation, he presented with obstructive ileus. Monthly assessment with transthoracic echocardiography (TTE) did not document any abnormalities around the ventricle. A contrast computed tomographic (CT) scan revealed a huge apical aneurysm protruding into the preperitoneal space. The aneurysm oppressed the transverse colon, resulting in obstructive ileus. Aneurysmectomy was carried out and MRSA was identified from the resected tissue. We reached the precise diagnosis with a CT-scan, although routine assessment with TTE failed to reveal abnormalities. Knowledge of this complication is essential in LVAS management. This is certainly rare, but possibly occurs in all the patients on prolonged LVAS support. Early and accurate diagnosis together with aggressive intervention would bring favorable outcome in such serious cases.
使用左心室辅助系统(LVAS)进行长期支持会增加与设备相关感染的风险。我们遇到了LVAS的一种罕见并发症:心尖插管处的感染性动脉瘤,其表现不典型。一名27岁男性,扩张型心肌病急性加重,接受了体外型LVAS治疗。六个月后,患者发生耐甲氧西林金黄色葡萄球菌(MRSA)败血症,尽管进行了强化抗生素治疗,但仍持续了长达三个月。植入后17个月,他出现了肠梗阻。每月经胸超声心动图(TTE)评估未发现心室周围有任何异常。对比计算机断层扫描(CT)显示一个巨大的心尖动脉瘤突入腹膜前间隙。动脉瘤压迫横结肠,导致肠梗阻。进行了动脉瘤切除术,并从切除组织中鉴定出MRSA。尽管TTE的常规评估未能发现异常,但我们通过CT扫描做出了准确诊断。了解这种并发症对于LVAS的管理至关重要。这当然很罕见,但可能发生在所有接受长期LVAS支持的患者中。在这种严重情况下,早期准确诊断并积极干预将带来良好的结果。