• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Insulin-regulated glucagon-like peptide-1 release from L cells: actin' out.

作者信息

Thurmond Debbie C

机构信息

Departments of Pediatrics,Basic Diabetes Group of the Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.

出版信息

Endocrinology. 2009 Dec;150(12):5202-4. doi: 10.1210/en.2009-1178.

DOI:10.1210/en.2009-1178
PMID:19933397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2795704/
Abstract
摘要

相似文献

1
Insulin-regulated glucagon-like peptide-1 release from L cells: actin' out.胰岛素调节L细胞中胰高血糖素样肽-1的释放：肌动蛋白发挥作用。
Endocrinology. 2009 Dec;150(12):5202-4. doi: 10.1210/en.2009-1178.
2
The rho guanosine 5'-triphosphatase, cell division cycle 42, is required for insulin-induced actin remodeling and glucagon-like peptide-1 secretion in the intestinal endocrine L cell.rho 鸟苷酸 5'-三磷酸酶、细胞分裂周期蛋白 42 在胰岛素诱导的肠道内分泌 L 细胞肌动蛋白重塑和胰高血糖素样肽-1 分泌中是必需的。
Endocrinology. 2009 Dec;150(12):5249-61. doi: 10.1210/en.2009-0508. Epub 2009 Oct 9.
3
Bitter tastant quinine modulates glucagon-like peptide-1 exocytosis from clonal GLUTag enteroendocrine L cells via actin reorganization.苦味剂奎宁通过肌动蛋白重组调节克隆 GLUTag 肠内分泌 L 细胞中的胰高血糖素样肽-1 胞吐作用。
Biochem Biophys Res Commun. 2018 Jun 7;500(3):723-730. doi: 10.1016/j.bbrc.2018.04.143. Epub 2018 Apr 25.
4
Bacterial metabolite S-equol modulates glucagon-like peptide-1 secretion from enteroendocrine L cell line GLUTag cells via actin polymerization.细菌代谢产物 S-雌马酚通过肌动蛋白聚合调节肠内分泌 L 细胞系 GLUTag 细胞分泌胰高血糖素样肽-1。
Biochem Biophys Res Commun. 2018 Jul 2;501(4):1009-1015. doi: 10.1016/j.bbrc.2018.05.100. Epub 2018 May 21.
5
Oleoyl-lysophosphatidylinositol enhances glucagon-like peptide-1 secretion from enteroendocrine L-cells through GPR119.油酰基溶血磷脂酰肌醇通过 GPR119 增强肠内分泌 L 细胞胰高血糖素样肽-1 的分泌。
Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Sep;1863(9):1132-1141. doi: 10.1016/j.bbalip.2018.06.007. Epub 2018 Jun 5.
6
Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine.在小鼠中抑制 RHOA 信号通路可增加肠道葡萄糖耐量和肠内分泌细胞及其他分泌细胞的数量。
Gastroenterology. 2018 Oct;155(4):1164-1176.e2. doi: 10.1053/j.gastro.2018.06.039. Epub 2018 Jun 20.
7
Evidence for paracrine/autocrine regulation of GLP-1-producing cells.GLP-1 分泌细胞的旁分泌/自分泌调节证据。
Am J Physiol Cell Physiol. 2013 Nov 15;305(10):C1041-9. doi: 10.1152/ajpcell.00227.2013. Epub 2013 Aug 28.
8
Insulin regulates glucagon-like peptide-1 secretion from the enteroendocrine L cell.胰岛素调节肠内分泌L细胞分泌胰高血糖素样肽-1。
Endocrinology. 2009 Feb;150(2):580-91. doi: 10.1210/en.2008-0726. Epub 2008 Sep 25.
9
Nutritional regulation of glucagon-like peptide-1 secretion.胰高血糖素样肽-1分泌的营养调节
J Physiol. 2009 Jan 15;587(1):27-32. doi: 10.1113/jphysiol.2008.164012. Epub 2008 Nov 10.
10
Insulin-increased prolactin gene expression requires actin treadmilling: potential role for p21 activated kinase.胰岛素增加催乳素基因表达需要肌动蛋白踏车运动：p21激活激酶的潜在作用。
Endocrinology. 2007 Dec;148(12):5874-83. doi: 10.1210/en.2007-0127. Epub 2007 Sep 20.

引用本文的文献

1
Elevated circulating fasting glucagon-like peptide-1 in surgical patients with aortic valve disease and diabetes.主动脉瓣疾病合并糖尿病手术患者循环中空腹胰高血糖素样肽-1水平升高。
Diabetol Metab Syndr. 2017 Oct 10;9:79. doi: 10.1186/s13098-017-0279-0. eCollection 2017.
2
Glucagon-like peptide-1 secreting cell function as well as production of inflammatory reactive oxygen species is differently regulated by glycated serum and high levels of glucose.胰高血糖素样肽-1 分泌细胞的功能以及炎症反应性活性氧的产生受到糖化血清和高葡萄糖水平的不同调节。
Mediators Inflamm. 2014;2014:923120. doi: 10.1155/2014/923120. Epub 2014 Feb 4.
3
Cellular biophysical dynamics and ion channel activities detected by AFM-based nanorobotic manipulator in insulinoma β-cells.基于原子力显微镜的纳米机器人操纵器检测到的胰岛 β 细胞的细胞生物物理动力学和离子通道活性。
Nanomedicine. 2013 Jul;9(5):636-45. doi: 10.1016/j.nano.2012.10.011. Epub 2012 Nov 22.
4
Gene targeting implicates Cdc42 GTPase in GPVI and non-GPVI mediated platelet filopodia formation, secretion and aggregation.基因靶向表明 Cdc42 GTP 酶参与了 GPVI 和非-GPVI 介导的血小板丝状伪足形成、分泌和聚集。
PLoS One. 2011;6(7):e22117. doi: 10.1371/journal.pone.0022117. Epub 2011 Jul 18.

本文引用的文献

1
The rho guanosine 5'-triphosphatase, cell division cycle 42, is required for insulin-induced actin remodeling and glucagon-like peptide-1 secretion in the intestinal endocrine L cell.rho 鸟苷酸 5'-三磷酸酶、细胞分裂周期蛋白 42 在胰岛素诱导的肠道内分泌 L 细胞肌动蛋白重塑和胰高血糖素样肽-1 分泌中是必需的。
Endocrinology. 2009 Dec;150(12):5249-61. doi: 10.1210/en.2009-0508. Epub 2009 Oct 9.
2
Imaging exocytosis of single glucagon-like peptide-1 containing granules in a murine enteroendocrine cell line with total internal reflection fluorescent microscopy.用全内反射荧光显微镜成像小鼠肠内分泌细胞系中单个含胰高血糖素样肽-1颗粒的胞吐作用。
Biochem Biophys Res Commun. 2009 Dec 4;390(1):16-20. doi: 10.1016/j.bbrc.2009.09.043. Epub 2009 Sep 18.
3
TGR5-mediated bile acid sensing controls glucose homeostasis.TGR5介导的胆汁酸感知调控葡萄糖稳态。
Cell Metab. 2009 Sep;10(3):167-77. doi: 10.1016/j.cmet.2009.08.001.
4
Identification of a distal GLUT4 trafficking event controlled by actin polymerization.鉴定由肌动蛋白聚合作用控制的GLUT4远端转运事件。
Mol Biol Cell. 2009 Sep;20(17):3918-29. doi: 10.1091/mbc.e09-03-0187. Epub 2009 Jul 15.
5
Incretin-based therapies for type 2 diabetes mellitus.用于2型糖尿病的基于肠促胰岛素的疗法。
Nat Rev Endocrinol. 2009 May;5(5):262-9. doi: 10.1038/nrendo.2009.48.
6
Mechanisms of biphasic insulin-granule exocytosis - roles of the cytoskeleton, small GTPases and SNARE proteins.双相胰岛素颗粒胞吐作用机制——细胞骨架、小GTP酶和SNARE蛋白的作用
J Cell Sci. 2009 Apr 1;122(Pt 7):893-903. doi: 10.1242/jcs.034355.
7
Impaired insulin exocytosis in neural cell adhesion molecule-/- mice due to defective reorganization of the submembrane F-actin network.神经细胞黏附分子基因敲除小鼠中，由于膜下F-肌动蛋白网络重组缺陷导致胰岛素胞吐受损。
Endocrinology. 2009 Jul;150(7):3067-75. doi: 10.1210/en.2008-0475. Epub 2009 Feb 12.
8
Nutritional regulation of glucagon-like peptide-1 secretion.胰高血糖素样肽-1分泌的营养调节
J Physiol. 2009 Jan 15;587(1):27-32. doi: 10.1113/jphysiol.2008.164012. Epub 2008 Nov 10.
9
Insulin regulates glucagon-like peptide-1 secretion from the enteroendocrine L cell.胰岛素调节肠内分泌L细胞分泌胰高血糖素样肽-1。
Endocrinology. 2009 Feb;150(2):580-91. doi: 10.1210/en.2008-0726. Epub 2008 Sep 25.
10
Filamentous actin regulates insulin exocytosis through direct interaction with Syntaxin 4.丝状肌动蛋白通过与 Syntaxin 4 的直接相互作用来调节胰岛素胞吐作用。
J Biol Chem. 2008 Apr 18;283(16):10716-26. doi: 10.1074/jbc.M709876200. Epub 2008 Feb 19.