Step D L, Blue J T, Dill S G
Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University Ithaca 14853.
Cornell Vet. 1991 Jan;81(1):13-8.
Acute, severe hemolytic anemia occurred in a horse being treated for tetanus with intravenous penicillin and tetanus antitoxin. During treatment, the horse developed a positive direct antiglobulin test and a high titer (maximum 1:1024) of IgG anti-penicillin antibody. The horse recovered from the tetanus and penicillin induced hemolytic anemia, but later developed acute hepatic failure, probably resulting from the administration of equine origin tetanus antitoxin.
