Prokopiw I, Hynna-Liepert T T, Dinda P K, Prentice R S, Beck I T
Department of Medicine, Queen's University, Hotel Dieu Hospital, Kingston, Ontario, Canada.
Gastroenterology. 1991 Mar;100(3):638-47. doi: 10.1016/0016-5085(91)80007-v.
To investigate whether there is a difference in the microvascular architecture between the body and the antrum of the canine stomach, these two locations were compared with respect to microsphere entrapment and the microvascular architecture and diameter in relation to histology by corrosion casting and by intraarterial injection of india ink. There was 63% shunting of 9-micron microspheres in the antrum, but none in the body. Corrosion cast and Indian ink studies showed that in the body there was a single microvascular network of capillaries that appeared to originate from the arterioles in the submucosa and were in close apposition to the epithelial cells of the gastric glands. The diameter of these capillaries was 8.6 +/- 0.2 microns. In contrast, there were two distinct capillary networks in the antrum: a basal and a superficial. The capillaries of the basal network of the antrum originated from the arterioles at the level of the muscularis mucosa and drained into the capillaries of the superficial mucosa. The capillaries of the superficial network had a significantly larger diameter (10.8 +/- 0.4 microns) than those of the basal network (7.3 +/- 0.2 microns). In many instances the capillaries of the superficial network originated directly from the ascending arterioles passing through the basal network. These direct arteriocapillary connections may have permitted the shunting of 9-microns spheres in the antrum.
为了研究犬胃体部和胃窦部的微血管结构是否存在差异，通过铸型腐蚀法和动脉内注射印度墨水，对这两个部位的微球截留情况、微血管结构以及与组织学相关的微血管直径进行了比较。胃窦部9微米微球的分流率为63%，而胃体部则无分流。铸型腐蚀和印度墨水研究表明，胃体部有一个单一的毛细血管微血管网络，似乎起源于黏膜下层的小动脉，并与胃腺的上皮细胞紧密相邻。这些毛细血管的直径为8.6±0.2微米。相比之下，胃窦部有两个不同的毛细血管网络：一个是基部网络，一个是表层网络。胃窦部基部网络的毛细血管起源于黏膜肌层水平的小动脉，并汇入表层黏膜的毛细血管。表层网络的毛细血管直径（10.8±0.4微米）明显大于基部网络的毛细血管直径（7.3±0.2微米）。在许多情况下，表层网络的毛细血管直接起源于穿过基部网络的升支小动脉。这些直接的动脉 - 毛细血管连接可能导致了胃窦部9微米微球的分流。
