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冠状动脉介入治疗(CAS):何种病变选用何种支架。

CAS: which stent for which lesion.

作者信息

Müller-Hülsbeck S, Preuss H, Elhöft H

机构信息

Department of Diagnostic and Interventional Radiology/Neuroradiology Academic Hospitals Flensburg, Flensburg, Germany.

出版信息

J Cardiovasc Surg (Torino). 2009 Dec;50(6):767-72.

Abstract

Current carotid stent designs and their attributes like scaffolding to reduce plaque prolapses and embolization, flexibility, adaptability and conformability to the vessel vary largely. Knowing that differences in behaviour due to stent design exist, especially due to the open cell design (which show high flexibility and therefore adaptability to the vessel but allows in theory easy particle penetration due to open structure) and closed cell designs (which show low flexibility and therefore low adaptability to the vessel but show high resistance to particle penetration due to closed cell design and high scaffolding), physicians have to be aware of these differences when planning carotid artery stenting procedures. The individual characteristics of each stent device may make it an attractive choice in one circumstance but render it less desirable in other situations; in approximately 75% of all procedures, all types of stents will achieve similar outcomes, making adequate device selection unnecessary; for the remaining quarter, careful preoperative screening is mandatory. The aim of this article was to review different stents with regard to latest designs intended for carotid stenting with regard to topics as mentioned above highlighting latest developments in specific designs especially developed for carotid lesion treatment.

摘要

目前的颈动脉支架设计及其特性,如用于减少斑块脱垂和栓塞的支架结构、柔韧性、对血管的适应性和贴合性等,差异很大。鉴于支架设计会导致行为差异,特别是开放细胞设计(显示出高柔韧性,因此对血管具有适应性,但由于开放结构理论上允许颗粒容易穿透)和封闭细胞设计(显示出低柔韧性,因此对血管的适应性低,但由于封闭细胞设计和高支架结构而对颗粒穿透具有高抵抗力),医生在规划颈动脉支架置入手术时必须了解这些差异。每个支架装置的个体特性可能使其在一种情况下成为有吸引力的选择,但在其他情况下则不太理想;在所有手术中,约75%的情况下,所有类型的支架都将取得相似的结果,因此无需进行适当的装置选择;对于其余四分之一的情况,术前仔细筛查是必不可少的。本文的目的是就上述主题,回顾针对颈动脉支架置入的最新设计的不同支架,突出特别为颈动脉病变治疗而开发的特定设计的最新进展。

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