Dahl Torbjørn, Ellekjaer Hanne
Karkirugisk avdeling, St. Olavs hospital, 7006 Trondheim og Institutt for sirkulasjon og bildediagnostikk, Norges teknisk-naturvitenskapelige universitet, Norway.
Tidsskr Nor Laegeforen. 2009 Nov 19;129(22):2374-7. doi: 10.4045/tidsskr.09.0274.
About 12,000 people suffer an ischemic stroke in Norway every year; 20 % of them may be caused by emboli from precerebral arteries. We discuss the epidemiology of carotid artery stenoses and assessment upon suspicion, and provide an overview of medical treatment and indications for surgery.
The article is based on literature identified through non-systematic searches in PubMed, core medical journals and textbooks and the authors' experience from a vascular surgical department and stroke unit.
Stroke symptoms or recurrent transient ischemic attacks (TIAs) should lead to direct admission to hospital, while patients with single TIAs should be assessed as out-patients in a hospital within a few days. Risk-factors should be investigated, and the carotid arteries should be examined with duplex ultrasound upon suspicion of stenosis. There is only a weak correlation between a neck bruit and an ipsilateral carotid artery stenosis, but a connection can usually be clarified by use of duplex ultrasound. All patients with a carotid artery stenosis should have medical treatment to prevent complications of atherosclerotic disease; i.e. antithrombotic, and for the majority cholesterol-lowering treatment and possibly antihypertensive medication. Patients with a symptomatic carotid artery stenosis of more than 50 % diameter reduction should be considered for surgical treatment within 14 days. Surgery for asymptomatic carotid artery stenoses seems to have a marginal effect.
Patients with stroke-like symptoms should be examined by a doctor as soon as possible. Quick diagnosis and treatment of patients with cerebrovascular events is demanding for the logistics of our hospitals.
在挪威,每年约有12,000人发生缺血性中风;其中20%可能由脑前动脉的栓子引起。我们讨论了颈动脉狭窄的流行病学以及疑似病例的评估,并概述了药物治疗和手术指征。
本文基于通过在PubMed、核心医学期刊和教科书中进行非系统检索以及作者在血管外科和中风单元的经验所确定的文献。
中风症状或复发性短暂性脑缺血发作(TIA)应导致直接住院,而单次TIA患者应在数天内作为门诊患者在医院接受评估。应调查危险因素,疑似狭窄时应使用双功超声检查颈动脉。颈部杂音与同侧颈动脉狭窄之间仅有微弱的相关性,但通常可通过双功超声明确两者之间的联系。所有颈动脉狭窄患者均应接受药物治疗以预防动脉粥样硬化疾病的并发症;即抗血栓治疗,并且大多数患者应接受降胆固醇治疗,可能还需使用抗高血压药物。症状性颈动脉狭窄直径减少超过50%的患者应在14天内考虑手术治疗。无症状性颈动脉狭窄的手术似乎效果甚微。
有中风样症状的患者应尽快由医生进行检查。脑血管事件患者的快速诊断和治疗对我们医院的后勤工作要求很高。