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棉酚及其衍生物与人工膜脂基质的 PVP 配合物的相互作用。

The interaction of PVP complexes of gossypol and its derivatives with an artificial membrane lipid matrix.

机构信息

A.S. Sadykov Institute of Bioorganic Chemistry, Academy of Sciences of Uzbekistan, 83, st, Kh. Abdullaev, Tashkent, 100125, Uzbekistan.

出版信息

Cell Mol Biol Lett. 2010;15(1):98-117. doi: 10.2478/s11658-009-0037-x. Epub 2009 Nov 20.

Abstract

In this paper, we present the results of a study on the membrane-active properties of gossypol, its derivatives and their polyvinylpyrrolidone complexes as assessed by differential scanning calorimetry and by the fluorescent probe method. The latter revealed the change in polarization of the incident radiation caused by the action of the polyphenol on the artificial membrane lipid matrix.

摘要

本文通过差示扫描量热法和荧光探针法研究了棉酚、其衍生物及其聚乙烯吡咯烷酮复合物的膜活性性质。后者揭示了多酚对人工膜脂基质的作用引起入射辐射偏振的变化。

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Investigations on gossypol: past and present developments.棉酚研究:过去与现在的进展
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