Keitel W
Z Rheumatol. 2009 Dec;68(10):851-6. doi: 10.1007/s00393-009-0541-4.
The name of Sir Alfred Baring Garrod is linked with the first detection of uric acid in blood and its accumulation in sufferers from gout as well as the formulation of the term rheumatoid arthritis. The disease concept formulated by him initially (especially in Germany) caused confusion and much discussion but has now become accepted worldwide. Garrod's work on gout delivered important contributions to the elucidation of pathophysiological problems of the symptoms. Furthermore, he made a great contribution to the reorganization of the British Pharmacopoeia. One of his sons, the also knighted Sir Archibald Edward Garrod, initially continued the work of his father in the field of rheumatology and thereby made it really known. Later he developed his own research field with the establishment of the genetics of metabolism and introduced here the term inborn errors of metabolism.
阿尔弗雷德·巴林·加罗德爵士的名字与血液中尿酸的首次发现、痛风患者体内尿酸的积累以及类风湿性关节炎这一术语的提出联系在一起。他最初提出的疾病概念(尤其是在德国)引发了混乱和诸多讨论,但如今已被全世界所接受。加罗德关于痛风的研究为阐明该病症的病理生理问题做出了重要贡献。此外,他对《英国药典》的重新编纂也做出了巨大贡献。他的一个儿子,同样被封为爵士的阿奇博尔德·爱德华·加罗德爵士,最初在风湿病学领域延续了他父亲的工作,从而使这一领域真正为人所知。后来,他通过建立代谢遗传学发展了自己的研究领域,并在此引入了“先天性代谢缺陷”这一术语。