Marson P, Pasero G
Apheresis Unit, Blood Transfusion Service, University Hospital of Padova, Italy.
Reumatismo. 2012 Jan 19;63(4):199-206. doi: 10.4081/reumatismo.2011.199.
The history of microcrystalline arthritis only began in 1961 when Daniel McCarty and Joseph Lee Hollander demonstrated the presence of sodium monourate crystals in the synovial fluid of gouty patients. However, gout is a historical disease, thanks to the descriptions of Hippocrates, Caelius Aurelianus, Soranus of Ephesus and Araeteus of Cappadocia. The relationship between hyperuricemia and gout was first documented in the nineteenth century by Alfred Baring Garrod, who demonstrated deposits of uric acid crystals on a linen thread held dipped in acidified blood (the so-called "thread method"). Gout has always been considered a prerogative of the moneyed classes (arthritis divitum), and history is full of famous gouty personalities, including kings, emperors, popes, commanders, politicians, artists, writers, philosophers and scientists. Another form of microcrystalline arthritis, chondrocalcinosis, was identified as being a rheumatic disorder different from gout in the 1960s. As a specific clinical entity, it was first identified in 1958 by Dušan Žitnˇan and Štefan Sit'aj in a few Slovak families.
微晶性关节炎的历史始于1961年，当时丹尼尔·麦卡蒂和约瑟夫·李·霍兰德在痛风患者的滑液中发现了单钠尿酸盐晶体。然而，痛风是一种历史悠久的疾病，这要归功于希波克拉底、凯利乌斯·奥雷利安努斯、以弗所的索拉努斯和卡帕多西亚的阿雷泰乌斯的描述。高尿酸血症与痛风之间的关系最早在19世纪由阿尔弗雷德·巴林·加罗德记录，他在浸于酸化血液中的亚麻线上展示了尿酸晶体的沉积（所谓的“线法”）。痛风一直被认为是有钱阶层的特权（富贵病性关节炎），历史上有许多著名的痛风患者，包括国王、皇帝、教皇、指挥官、政治家、艺术家、作家、哲学家和科学家。微晶性关节炎的另一种形式——软骨钙质沉着症，在20世纪60年代被确认为一种不同于痛风的风湿性疾病。作为一种特定的临床实体，它于1958年由杜尚·日特南和斯特凡·西塔伊在一些斯洛伐克家庭中首次发现。
