Division of Cardiology, Department of Medicine, Queen Mary Hospital, Hong Kong, China.
Catheter Cardiovasc Interv. 2010 Feb 15;75(3):345-8. doi: 10.1002/ccd.22294.
We evaluated the long term clinical outcomes of femoral vascular closure devices following its deployment in coronary angiography and percutaneous coronary intervention (PCI) procedures.
From June 2000 to September 2004, 265 patients who received femoral vascular closure devices after coronary angiography and PCIs were enrolled into the study. Patients' medical records were reviewed and vascular complications within 1 year of follow-up period were recorded. Rutherford's categories of claudication were used to quantify different degrees of claudication and leg ischaemia. Duplex ultrasonography of both femoral arteries (using the nonaccessed site as control) was performed at 1 year after deployment of vascular closure devices. Vessel diameter and flow velocities for both common femoral arteries were obtained.
There was no occurrence of late vascular complications like arteriovenous fistula, pseudoaneurysm, surgical repair of access site complications, late groin bleeding and infection. By Rutherford categories of claudication, 99.2% of patients had grade 0 claudication while the remaining 0.8% was in grade 1. By arterial Duplex ultrasonography, the peak systolic velocity of the accessed femoral artery (predominantly right side) was nonsignificantly higher, 94.9 + or - 26.0 cm/s when compared to 91.5 + or - 24.8 cm/s in the control site (P = 0.12). As for vessel diameter, no significant difference was found in the mean end-diastolic vessel diameter 8.8 + or - 1.3 mm (puncture site) versus 8.7 + or - 4.4 mm (control site) (P = 0.72).
We found that the use of femoral closure devices was safe and it was not associated with any adverse long term vascular complications.
我们评估了在冠状动脉造影和经皮冠状动脉介入治疗（PCI）后使用股血管闭合装置的长期临床结果。
2000 年 6 月至 2004 年 9 月，对 265 例在冠状动脉造影和 PCI 后接受股血管闭合装置治疗的患者进行了研究。回顾患者的病历记录，并记录随访期内 1 年内的血管并发症。采用 Rutherford 跛行分类标准来量化不同程度的跛行和腿部缺血。在股血管闭合装置植入 1 年后，对双侧股动脉（使用未穿刺部位作为对照）进行双功超声检查。获得双侧股总动脉的血管直径和血流速度。
无晚期血管并发症发生，如动静脉瘘、假性动脉瘤、血管穿刺部位并发症的手术修复、迟发性腹股沟出血和感染。根据 Rutherford 跛行分类标准，99.2%的患者跛行程度为 0 级，其余 0.8%为 1 级。经动脉双功超声检查，股动脉（主要为右侧）收缩期峰值流速为 94.9 ± 26.0cm/s，与对照组的 91.5 ± 24.8cm/s 相比无显著差异（P = 0.12）。对于血管直径，在平均舒张末期血管直径 8.8 ± 1.3mm（穿刺部位）与 8.7 ± 4.4mm（对照组）之间未发现显著差异（P = 0.72）。
我们发现使用股血管闭合装置是安全的，它与任何不良的长期血管并发症无关。
