Division of Transplantation, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Liver Transpl. 2009 Dec;15(12):1671-5. doi: 10.1002/lt.21944.
Adult-to-adult living donor liver transplantation is an accepted treatment option for patients with end-stage liver disease. It is generally acknowledged that a graft weight to recipient body weight ratio > 0.8 is required in order to prevent the development of small-for-size syndrome. Size mismatch, however, is not the only factor responsible for the syndrome; instead, it results from a combination of factors, including the size, recipient status, and degree of portal hypertension. The ability to modulate the portal venous inflow has sparked renewed interest in the left lobe graft. We have used the hemiportocaval shunt, as described by Troisi et al. (Am J Transplant 2005;5:1397-1404), in left lobe living donor liver transplants in order to prevent small-for-size syndrome while enhancing the safety of the donor operation. In this report, we describe a novel technique for occluding a hemiportocaval shunt in a patient who developed hepatic encephalopathy after receiving a small-for-size left lobe liver allograft from a living donor.
成人对成人活体肝移植是治疗终末期肝病患者的一种公认的治疗选择。一般认为,为了防止小肝综合征的发生,移植物与受者体重的比值>0.8。然而,大小不匹配并不是导致该综合征的唯一因素;相反,它是多种因素共同作用的结果,包括肝脏的大小、受者的状况和门静脉高压的程度。调节门静脉流入的能力激发了人们对左外叶供肝的新兴趣。我们使用了 Troisi 等人描述的半门静脉-腔静脉分流术(Am J Transplant 2005;5:1397-1404),用于预防小肝综合征,同时提高供者手术的安全性。在本报告中,我们描述了一种在接受小体积左外叶活体肝移植后发生小肝综合征的患者中,闭合半门静脉-腔静脉分流术的新技术。