Shubchyns'kyĭ V V, Varbanets' L D
Mikrobiol Z. 2009 Mar-Apr;71(2):27-34.
Effect of lipopolysaccharides (LPS) and their structure components (lipid A, oligosaccharide core, and O-specific polysaccharides) from 8 strains of P. fontium on the adhesion process have been investigated for the first time. It was demonstrated, that LPS and their structural components may compete with E. coli adhesins and phytohemagglutinin under binding with receptors on the surface of the rabbit erythrocytes. An analysis of different structural components influence indicated, that in comparison with O-specific polysaccharides and core oligosaccharide lipids A of all investigated strains of P. fontium displayed the highest inhibitory action on the adhesion process. It was shown that there existed certain dependence between LPS composition and their effects on the adhesion process. LPS, obtained from P. fontium strains grown at different temperatures (36, 25, 4 degrees C) and characterized by various quantitative and qualitative monosaccharide and fatty acid composition, demonstrated different adhesion properties.
首次研究了来自8株丰氏普罗威登斯菌的脂多糖（LPS）及其结构成分（脂质A、寡糖核心和O-特异性多糖）对黏附过程的影响。结果表明，LPS及其结构成分在与兔红细胞表面受体结合时可能与大肠杆菌黏附素和植物血凝素竞争。对不同结构成分影响的分析表明，与所有研究的丰氏普罗威登斯菌菌株的O-特异性多糖和核心寡糖相比，脂质A对黏附过程表现出最高的抑制作用。结果表明，LPS组成与其对黏附过程的影响之间存在一定的相关性。从在不同温度（36、25、4℃）下生长的丰氏普罗威登斯菌菌株获得的LPS，其具有各种定量和定性的单糖和脂肪酸组成，表现出不同的黏附特性。
