Lee Dong-Hee
Department of Otolaryngology-Head and Neck Surgery, Uijeongbu St Mary's Hospital, The Catholic University of Korea, College of Medicine, #65-1 Geumo-Dong, Uijeongbu City, Gyeonggi-Do, Seoul 480-717, Republic of Korea.
Int J Pediatr Otorhinolaryngol. 2010 Feb;74(2):151-3. doi: 10.1016/j.ijporl.2009.10.029. Epub 2009 Nov 25.
To determine the accuracy of pneumatic otoscopy, a tympanogram and otomicroscopy for diagnosing otitis media with effusion (OME) in a pediatric population.
Prospective blinded clinical and IRB-approved study at a secondary referral hospital. SUBJECTIVE AND METHODS: Eighty-one children (155 ears) were recruited for this study, who were referred to my secondary referral hospital after OME was diagnosed at other primary clinics. The examiner was blinded for the findings of the diagnostic tools. Myringotomy under local anesthesia was used as the diagnostic reference standard. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of the three diagnostic tools were calculated.
Otomicroscopy was the most sensitive and specific tool among the three diagnostic tools. Otomicroscopy showed the best agreement with myringotomy (kappa=0.784).
Otomicroscopy can make a more accurate diagnosis even for children who are seen at an outpatient clinic. The much higher specificity of otomicroscopy makes it the best confirmative test and its much higher positive predictive value can prevent a late diagnosis of OME, which can result in severe sequelae.
确定气耳镜检查、鼓室图检查和耳显微镜检查在诊断儿童中耳积液(OME)方面的准确性。
在一家二级转诊医院进行的前瞻性盲法临床研究,并获得了机构审查委员会(IRB)的批准。
招募了81名儿童(155只耳朵)参与本研究,这些儿童在其他基层诊所被诊断为OME后转诊至我院。检查者对诊断工具的结果不知情。以局部麻醉下的鼓膜切开术作为诊断参考标准。计算了三种诊断工具的敏感性、特异性、阳性预测值、阴性预测值和准确性。
耳显微镜检查是三种诊断工具中最敏感和特异的工具。耳显微镜检查与鼓膜切开术的一致性最佳(kappa = 0.784)。
即使对于门诊就诊的儿童,耳显微镜检查也能做出更准确的诊断。耳显微镜检查更高的特异性使其成为最佳的确诊检查,其更高的阳性预测值可防止OME的延迟诊断,而OME延迟诊断可能导致严重的后遗症。