evidENT, Ear Institute, University College London, Royal National Throat Nose and Ear Hospital, 330 Grays Inn Road, WC1X 8DA London, UK.
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
Nat Rev Dis Primers. 2016 Sep 8;2(1):16063. doi: 10.1038/nrdp.2016.63.
Otitis media (OM) or middle ear inflammation is a spectrum of diseases, including acute otitis media (AOM), otitis media with effusion (OME; 'glue ear') and chronic suppurative otitis media (CSOM). OM is among the most common diseases in young children worldwide. Although OM may resolve spontaneously without complications, it can be associated with hearing loss and life-long sequelae. In developing countries, CSOM is a leading cause of hearing loss. OM can be of bacterial or viral origin; during 'colds', viruses can ascend through the Eustachian tube to the middle ear and pave the way for bacterial otopathogens that reside in the nasopharynx. Diagnosis depends on typical signs and symptoms, such as acute ear pain and bulging of the tympanic membrane (eardrum) for AOM and hearing loss for OME; diagnostic modalities include (pneumatic) otoscopy, tympanometry and audiometry. Symptomatic management of ear pain and fever is the mainstay of AOM treatment, reserving antibiotics for children with severe, persistent or recurrent infections. Management of OME largely consists of watchful waiting, with ventilation (tympanostomy) tubes primarily for children with chronic effusions and hearing loss, developmental delays or learning difficulties. The role of hearing aids to alleviate symptoms of hearing loss in the management of OME needs further study. Insertion of ventilation tubes and adenoidectomy are common operations for recurrent AOM to prevent recurrences, but their effectiveness is still debated. Despite reports of a decline in the incidence of OM over the past decade, attributed to the implementation of clinical guidelines that promote accurate diagnosis and judicious use of antibiotics and to pneumococcal conjugate vaccination, OM continues to be a leading cause for medical consultation, antibiotic prescription and surgery in high-income countries.
中耳炎(OM)或中耳炎症是一种疾病谱,包括急性中耳炎(AOM)、分泌性中耳炎(OME;“胶耳”)和慢性化脓性中耳炎(CSOM)。OM 是全世界幼儿中最常见的疾病之一。尽管 OM 可能自行缓解而无并发症,但它可能与听力损失和终身后遗症有关。在发展中国家,CSOM 是听力损失的主要原因。OM 可由细菌或病毒引起;在“感冒”期间,病毒可通过咽鼓管向上蔓延至中耳,并为潜伏在鼻咽部的细菌耳病原体铺平道路。诊断取决于典型的体征和症状,例如 AOM 的急性耳痛和鼓膜(鼓膜)隆起以及 OME 的听力损失;诊断方法包括(气动)耳镜检查、鼓室图和声导抗测试。AOM 的主要治疗方法是对症治疗耳痛和发热,保留抗生素用于严重、持续或反复感染的儿童。OME 的管理主要包括观察等待,对于慢性积液、听力损失、发育迟缓或学习困难的儿童,主要采用鼓膜置管(鼓膜切开术)。需要进一步研究助听器在 OME 管理中缓解听力损失症状的作用。为了预防复发,反复 AOM 常采用鼓膜置管和腺样体切除术,但它们的有效性仍存在争议。尽管过去十年 OM 的发病率有所下降,这归因于临床指南的实施,这些指南促进了准确诊断和合理使用抗生素以及肺炎球菌结合疫苗,但 OM 仍然是高收入国家医疗咨询、抗生素处方和手术的主要原因。