Martinaud C, Gaillard T, Pons S, Fournier B, Brisou P
Service de dermatologie, Fédération des laboratoires HIA Sainte Anne, Toulon.
Ann Biol Clin (Paris). 2009 Nov-Dec;67(6):701-4. doi: 10.1684/abc.2009.0382.
We present a 73-year-old woman presented to our hospital with a 2 years history of eyes itching. The ophthalmological testing was normal. Physical examination revealed blepharitis and lesions acnea-like on mouth, nose and chest. Biological testing revealed no abnormalities. Histologic study and direct immunofluorescence on a cutaneous biopsy were no contributive. The research of an allergic origine was practised by cutaneous and serological tests and negative. An examination of eyelashes was performed and yielded Demodex. Demodex folliculorum is a mite that is the most common permanent ectoparasite of humans, which is thought to be linked to blepharitis and allergic blepharoconjunctivis with rosacea, although much controversy persists. Recent studies demonstrate a high frequence of chronic blepharitis when Demodex are abundant. Several molecules can be used to treat this infestation. Parasiticide as oral ivermectine may be useful when the infestation is important.
我们报告了一位73岁女性，因眼部瘙痒2年前来我院就诊。眼科检查正常。体格检查发现睑缘炎以及口腔、鼻部和胸部类似痤疮的病变。生物学检查未发现异常。皮肤活检的组织学研究和直接免疫荧光检查无诊断价值。通过皮肤和血清学检查进行的变应原研究结果为阴性。对睫毛进行检查发现了蠕形螨。毛囊蠕形螨是人类最常见的永久性体表寄生虫，虽然仍存在很多争议，但人们认为它与睑缘炎以及伴有酒渣鼻的变应性睑结膜炎有关。最近的研究表明，当蠕形螨数量较多时，慢性睑缘炎的发生率较高。有几种药物可用于治疗这种感染。当感染严重时，口服伊维菌素等杀寄生虫剂可能有效。
