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穿透性角膜移植术的半高帽状伤口构型:1年结果

Half top hat wound configuration for penetrating keratoplasty: 1-year results.

作者信息

Kaiserman I, Bahar I, Slomovic A R, Rootman D S

机构信息

Department of Ophthalmology, Barzilai Medical Center, Ashkelon 78306, Israel.

出版信息

Br J Ophthalmol. 2009 Dec;93(12):1629-33. doi: 10.1136/bjo.2008.156836.

Abstract

AIMS

To compare the 1-year outcomes after half-top-hat (HTH) penetrating keratoplasty (PK) versus top-hat (TH) PK and regular PK.

METHODS

We reviewed the clinical notes of 87 consecutive patients who had undergone either HTH PK (23 eyes), TH PK (36 eyes) or regular PK (35 eyes) at Toronto Western Hospital between 2002 and 2007. We evaluated best-corrected visual acuity (BCVA), topographic and refractive results, high-order ocular aberrations, endothelial cell counts and complication rates.

RESULTS

The three groups of patients did not differ significantly in their demographics (age, gender and laterality), donor endothelial cell counts, preoperative visual acuity or intraocular pressure (IOP). At 12 months postoperatively, BCVA was similar in the three groups, as was the mean spherical equivalent and cylinder. The time to sutures removal was significantly shorter in the HTH PK versus regular PK groups (3.8 (1.2) vs 9.7 (1.1) months, p<0.0001), and the endothelial cell counts were significantly higher (p = 0.003). The IOP was higher in the HTH PK patients than in regular PK patients (p = 0.04). All high-order aberrations tested were significantly higher in the HTH PK than in the regular PK groups (p<0.01). Regular PK had a higher rate of astigmatism treated with relaxing incisions (n = 7 vs n = 2 in HTH PK) and dehiscence of wound incision (n = 2, versus n = 0 in HTH PK).

CONCLUSIONS

BCVA and refractive results are similar after half-top-hat, top-hat and regular PK. Half-top-hat PK substantially speeds up visual recovery and contributes to significantly higher endothelial cell counts in the grafts 1 year after surgery.

摘要

目的

比较半高帽式(HTH)穿透性角膜移植术(PK)与高帽式(TH)PK及常规PK术后1年的疗效。

方法

我们回顾了2002年至2007年在多伦多西部医院连续接受HTH PK(23只眼)、TH PK(36只眼)或常规PK(35只眼)的87例患者的临床记录。我们评估了最佳矫正视力(BCVA)、地形图和屈光结果、高阶眼像差、内皮细胞计数和并发症发生率。

结果

三组患者在人口统计学特征(年龄、性别和眼别)、供体内皮细胞计数、术前视力或眼压(IOP)方面无显著差异。术后12个月,三组的BCVA相似,平均球镜等效度和柱镜也相似。HTH PK组与常规PK组相比,缝线拆除时间明显更短(3.8(1.2)个月对9.7(1.1)个月,p<0.0001),内皮细胞计数明显更高(p = 0.003)。HTH PK患者的IOP高于常规PK患者(p = 0.04)。所有检测的高阶像差在HTH PK组均显著高于常规PK组(p<0.01)。常规PK采用松解切口治疗散光的发生率更高(HTH PK组为7例对2例),伤口裂开的发生率也更高(常规PK组为2例,HTH PK组为0例)。

结论

半高帽式、高帽式和常规PK术后的BCVA和屈光结果相似。半高帽式PK可显著加快视力恢复,并使术后1年移植片的内皮细胞计数显著更高。

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