Vigovich Felix A, Hurt Mark A, Santa Cruz Daniel J
British Hospital of Buenos Aires, Buenos Aires, Argentina.
Am J Dermatopathol. 2010 Feb;32(1):76-8. doi: 10.1097/DAD.0b013e3181b119c6.
We report an unusual histopathological variant of a glomus tumor that arose in a peculiar topographic site, a sclerotic glomus tumor. Unlike conventional glomus tumors or glomangiomas that have a loose fibrous stroma with variable hyaline and myxoid changes, the case reported herein had a diffuse, hyalinized, sclerotic stroma. A further difference was that the majority of glomus tumors and glomangiomas occur in the subungual area, trunk, or extremities, whereas the present tumor occurred on the ear. Due to the peculiar histological features and location, other tumors were considered in the differential diagnosis to include Merkel cell carcinoma, primitive neuroectodermal tumor, and small cell melanoma. This article illustrates a unique variant of a glomus tumor, which to our knowledge has not been previously described.
我们报告了一种起源于特殊部位的不寻常组织病理学变异型的球瘤，即硬化性球瘤。与具有疏松纤维间质且伴有不同程度透明样和黏液样改变的传统球瘤或血管球瘤不同，本文报道的病例具有弥漫性、透明样变的硬化性间质。另一个不同之处在于，大多数球瘤和血管球瘤发生于甲下区域、躯干或四肢，而本病例发生于耳部。由于其特殊的组织学特征和位置，在鉴别诊断中考虑了其他肿瘤，包括默克尔细胞癌、原始神经外胚层肿瘤和小细胞黑色素瘤。本文阐述了一种独特的球瘤变异型，据我们所知，此前尚未有过相关描述。
