Hofman P A, Goris R J
Department of Surgery, University Hospital Nijmegen, The Netherlands.
J Trauma. 1991 Feb;31(2):261-3.
A retrospective study was performed to assess the effects on outcome of early osteosynthesis of major extremity fractures in patients with severe brain injury (GCS less than or equal to 7). In a consecutive series of 58 patients, early osteosynthesis was performed on the day of injury in 15 patients. (Group A). In 43 patients no major fractures were present or no early osteosynthesis was performed (Group B). The severity of brain injury as seen on CT scan was similar in both groups. Mortality was significantly lower in Group A, despite a significantly higher ISS. As to the functional end result of brain injury, an indication of a better outcome was present in Group A.
进行了一项回顾性研究，以评估严重脑损伤（格拉斯哥昏迷评分小于或等于7分）患者早期进行四肢主要骨折骨固定术对预后的影响。在连续的58例患者中，15例患者在受伤当天进行了早期骨固定术（A组）。43例患者无主要骨折或未进行早期骨固定术（B组）。两组患者CT扫描显示的脑损伤严重程度相似。尽管A组的损伤严重度评分显著更高，但其死亡率显著更低。关于脑损伤的功能最终结果，A组显示出更好预后的迹象。
