Department of Radiology and Biomedical Imaging, University of California-San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143, USA.
AJNR Am J Neuroradiol. 2010 Jun;31(6):1100-2. doi: 10.3174/ajnr.A1863. Epub 2009 Nov 26.
DWI was performed in fetuses with callosal agenesis and unilateral cortical malformations. ADC values were retrospectively measured in the developing white matter underlying the cortical malformation and compared with the corresponding contralateral white matter. In all 3 patients, ADC values were lower under the areas of cortical malformation compared with the normal contralateral side. Our findings suggest that there are structural differences in the developing white matter underlying areas of cortical malformation.
对合并胼胝体发育不全和单侧皮质发育不良的胎儿行 DWI 检查。对皮质发育不良下方的脑白质进行 ADC 值的回顾性测量,并与对侧相应脑白质进行比较。在所有 3 例患者中,皮质发育不良下方脑白质的 ADC 值均低于正常对侧。我们的研究结果提示皮质发育不良下方脑白质存在结构差异。