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脑畸形的弥散张量成像和纤维束追踪。

Diffusion tensor imaging and fiber tractography in brain malformations.

机构信息

Division of Pediatric Radiology, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, 600 N. Wolfe St., Nelson Basement, B-173, Baltimore, MD 21287-0842, USA.

出版信息

Pediatr Radiol. 2013 Jan;43(1):28-54. doi: 10.1007/s00247-012-2428-9. Epub 2013 Jan 4.

DOI:10.1007/s00247-012-2428-9
PMID:23288476
Abstract

Diffusion tensor imaging (DTI) is an advanced MR technique that provides qualitative and quantitative information about the micro-architecture of white matter. DTI and its post-processing tool fiber tractography (FT) have been increasingly used in the last decade to investigate the microstructural neuroarchitecture of brain malformations. This article aims to review the use of DTI and FT in the evaluation of a variety of common, well-described brain malformations, in particular by pointing out the additional information that DTI and FT renders compared with conventional MR sequences. In addition, the relevant existing literature is summarized.

摘要

弥散张量成像(DTI)是一种先进的磁共振技术,可提供关于白质微观结构的定性和定量信息。在过去十年中,DTI 及其后处理工具纤维束追踪(FT)越来越多地用于研究脑畸形的微观神经结构。本文旨在回顾 DTI 和 FT 在评估各种常见、描述明确的脑畸形中的应用,特别是通过指出 DTI 和 FT 与常规磁共振序列相比提供的额外信息。此外,还总结了相关的现有文献。

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本文引用的文献

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Evolutionarily assembled cis-regulatory module at a human ciliopathy locus.人类纤毛病相关基因座的进化组装顺式调控模块。
Science. 2012 Feb 24;335(6071):966-9. doi: 10.1126/science.1213506. Epub 2012 Jan 26.
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CEP41 is mutated in Joubert syndrome and is required for tubulin glutamylation at the cilium.CEP41 突变与杰氏综合征相关,并且对于纤毛中的微管蛋白谷氨酸化是必需的。
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Genotype-phenotype correlation in CC2D2A-related Joubert syndrome reveals an association with ventriculomegaly and seizures.
协调大脑皮质的构建和连接:放射状祖细胞的统一影响。
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A Proposed Clinical Classification and a Diagnostic Approach for Congenital Ataxias.先天性共济失调的临床分类及诊断方法建议
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The role of preoperative diffusion tensor imaging in predicting and improving functional outcome in pediatric patients undergoing epilepsy surgery: a systematic review.术前弥散张量成像在预测和改善癫痫手术患儿功能预后中的作用:一项系统评价
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Neuroimaging Findings in Patients with Mutations: Report of Two Cases.突变患者的神经影像学表现:两例报告。
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Structural connectivity of the human massa intermedia: A probabilistic tractography study.人类脑体中部的结构连接:一项概率性轨迹追踪研究。
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Genome-Wide Association Analysis of Neonatal White Matter Microstructure.全基因组关联分析新生儿脑白质微观结构。
Cereb Cortex. 2021 Jan 5;31(2):933-948. doi: 10.1093/cercor/bhaa266.
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AJNR Am J Neuroradiol. 2020 Aug;41(8):1495-1502. doi: 10.3174/ajnr.A6646. Epub 2020 Jul 30.
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Structural and Diffusion MRI Analyses With Histological Observations in Patients With Lissencephaly.无脑回畸形患者的结构和扩散磁共振成像分析与组织学观察
Front Cell Dev Biol. 2019 Jul 11;7:124. doi: 10.3389/fcell.2019.00124. eCollection 2019.
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Delineation and diagnostic criteria of Oral-Facial-Digital Syndrome type VI.口腔面指综合征 VI 型的界定和诊断标准。
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[Clinical application of diffusion tensor imaging and tractography in a child with holoprosencephaly].[弥散张量成像及纤维束成像在一名全前脑畸形患儿中的临床应用]
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Normal and abnormal development of the cerebellum and brainstem as depicted by diffusion tensor imaging.扩散张量成像所描绘的小脑和脑干的正常与异常发育
Semin Ultrasound CT MR. 2011 Dec;32(6):539-54. doi: 10.1053/j.sult.2011.06.005.
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