Takashima Tsutomu, Nakata Bunzo, Hatama Masahiro, Nomura Shinya, Komoto Masahiro, Ishikawa Tetsuro, Hirakawa Kosei
Department of Surgery, Osaka Socio-Medical Center, Osaka City University Graduate School of Medicine, Abeno-Ku, Osaka, Japan.
Int Surg. 2008 Sep-Oct;93(5):295-9.
A 62-year-old man presented with a painful left lateral neck mass. Aspiration cytology revealed lymph node metastasis of undifferentiated carcinoma. A Borrmann type 3 tumor was detected in the body of the stomach on endoscopic examination. No visceral metastasis was found. Distal gastrectomy and radical neck dissection were performed. Pathological examination revealed that the histological features of the gastric lesion were identical to those of the cervical lymph node lesion. Regional lymph nodes of the stomach and Virchow's lymph nodes were not involved. Irradiation to the left supraclavicular and cervical region and an oral tegafur anticancer agent (TS-1) were started. Left axillary and right supraclavicular lymphadenopathies were detected 4 and 5 months after surgery, respectively. Rapid progression of hoarseness was observed, and weekly docetaxcel was started. However, he died of airway obstruction 8 months after surgery.
一名62岁男性因左侧颈部疼痛性肿块就诊。细针穿刺细胞学检查显示为未分化癌淋巴结转移。内镜检查发现胃体部有Borrmann 3型肿瘤。未发现内脏转移。行远端胃切除术及根治性颈淋巴结清扫术。病理检查显示胃病变的组织学特征与颈部淋巴结病变相同。胃区域淋巴结和魏尔啸淋巴结未受累。开始对左锁骨上和颈部区域进行放疗,并口服替加氟抗癌药(TS-1)。术后4个月和5个月分别检测到左腋窝和右锁骨上淋巴结肿大。观察到声音嘶哑迅速进展,开始每周使用多西他赛。然而,他在术后8个月死于气道梗阻。