Militano Vincenzo, Muthu Sivakumar, Farooq Naheed, Sajjan Rakesh
Department of Nuclear Medicine, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom.
Department of General Surgery, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom.
World J Nucl Med. 2018 Oct-Dec;17(4):302-304. doi: 10.4103/wjnm.WJNM_82_17.
We are presenting the first case of a gastro-oesophageal junction adenocarcinoma with metastasis only to the intraparotid lymph node simulating Warthin's tumor. A 66-year-old man underwent an esophagogastroduodenoscopy that found circumferential ulcerated esophageal tumor beginning 40 cm from incisors resulting in stricture and two discrete erosions in the proximal third of esophagus. Biopsies from the stricture have demonstrated a poorly differentiated gastric adenocarcinoma. Computerized tomography (CT) confirmed the site of primary without evidence of distant metastasis. Positron emission tomography/CT showed high uptake in the known carcinoma in distal esophagus involving the gastro-oesophageal junction extending into the cardia of the stomach, the maximum standardized uptake value (SUV) 7.4. Furthermore, there was a focus of high-grade tracer activity, SUV 6.2, in the left intraparotid nodule which was initially thought to represent Warthin's tumor rather than metastasis; there was no evidence to suggest metastases elsewhere. Fine needle aspiration and biopsy from the enlarged intraparotid lymph node revealed that the histology was consistent with a poorly differentiated adenocarcinoma, metastasis from upper gastrointestinal tract.
我们报告首例仅转移至腮腺内淋巴结、酷似沃辛瘤的胃食管交界腺癌病例。一名66岁男性接受了食管胃十二指肠镜检查,发现距门齿40 cm处有一环形溃疡型食管肿瘤,导致食管狭窄,且在食管近端三分之一处有两处散在糜烂。狭窄部位活检显示为低分化胃腺癌。计算机断层扫描(CT)确定了原发部位,无远处转移证据。正电子发射断层扫描/CT显示,已知的远端食管腺癌累及胃食管交界并延伸至胃贲门处摄取高,最大标准化摄取值(SUV)为7.4。此外,左侧腮腺内结节有一处高代谢灶,SUV为6.2,最初认为是沃辛瘤而非转移灶;无其他部位转移的证据。对肿大的腮腺内淋巴结进行细针穿刺活检,结果显示组织学与低分化腺癌相符,为上消化道转移。