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[生发基质出血继发胎儿脑室扩大——病例报告]

[Fetal ventriculomegaly secondary to germinal matrix hemorrhage--case report].

作者信息

Zamłyński Jacek, Olejek Anita, Oleś Ewa, Herman-Sucharska Izabela, Sławska Helena, Bodzek Piotr, Paliga-Zytniewska Marta, Gajewska Alicja

机构信息

Katedra i Oddział Kliniczny Ginekologii, Połoznictwa i Ginekologii Onkologicznej w Bytomiu, Slaskiego Uniwersytetu Medycznego w Katowicach.

出版信息

Ginekol Pol. 2009 Oct;80(10):782-5.

Abstract

A germinal matrix is an area of the fetal brain where neuroblasts proliferate till the 20th week of gestation after which their migration takes place. Germinal matrix hemorrhage (GMH) is a frequent cause of fetal ventriculomegaly or hydrocephalus, yet the pathophysiological conditions of GMH remain unclear. A case of fetal ventriculomegaly resulting from GMH has been reported in the article. A prenatal ultrasonographic examination (US) carried out in the 30th week of gestation revealed enlarged ventricles. Utero magnetic resonance imaging (MRI) performed in the 34th week of gestation demonstrated asymetric ventriculomegaly and the changes suggesting the occurance of GMH and ependymal intraventricular hemorrhage. Fetal ventriculomegaly and hydrocephalus are commonly detected by ultrasonographic examination, but it is often difficult to determine the causes of the diseases by US. In these cases MRI allows to establish the final diagnosis.

摘要

生发基质是胎儿大脑中神经母细胞增殖的区域,直至妊娠第20周,之后神经母细胞开始迁移。生发基质出血(GMH)是胎儿脑室扩大或脑积水的常见原因,但其病理生理状况仍不清楚。本文报道了一例由GMH导致的胎儿脑室扩大病例。妊娠第30周进行的产前超声检查(US)显示脑室扩大。妊娠第34周进行的子宫磁共振成像(MRI)显示不对称脑室扩大以及提示GMH和脑室内室管膜下出血发生的变化。胎儿脑室扩大和脑积水通常通过超声检查发现,但通过超声往往难以确定病因。在这些情况下,MRI有助于做出最终诊断。

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