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PBOND:用于预测脯氨酸和非脯氨酸顺/反式异构化的网络服务器。

PBOND: web server for the prediction of proline and non-proline cis/trans isomerization.

机构信息

Unit of Medical Technology and Intelligent Information Systems, Department of Computer Science, University of loannina, loannina 45110, Greece.

出版信息

Genomics Proteomics Bioinformatics. 2009 Sep;7(3):138-42. doi: 10.1016/S1672-0229(08)60042-X.

DOI:10.1016/S1672-0229(08)60042-X
PMID:19944386
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5054403/
Abstract

PBOND is a web server that predicts the conformation of the peptide bond between any two amino acids. PBOND classifies the peptide bonds into one out of four classes, namely cis imide (cis-Pro), cis amide (cis-nonPro), trans imide (trans-Pro) and trans amide (trans-nonPro). Moreover, for every prediction a reliability index is computed. The underlying structure of the server consists of three stages: (1) feature extraction, (2) feature selection and (3) peptide bond classification. PBOND can handle both single sequences as well as multiple sequences for batch processing. The predictions can either be directly downloaded from the web site or returned via e-mail. The PBOND web server is freely available at http://195.251.198.21/pbond.html.

摘要

PBOND 是一个预测任意两个氨基酸之间肽键构象的网络服务器。PBOND 将肽键分为四类,即顺式酰亚胺(顺式-Pro)、顺式酰胺(顺式-nonPro)、反式酰亚胺(反式-Pro)和反式酰胺(反式-nonPro)。此外,对于每个预测,还计算了一个可靠性指标。该服务器的基础结构由三个阶段组成:(1)特征提取,(2)特征选择和(3)肽键分类。PBOND 可以处理单个序列和多个序列进行批处理。预测结果可以直接从网站下载,也可以通过电子邮件返回。PBOND 网络服务器可免费使用,网址为 http://195.251.198.21/pbond.html。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4eb/5054403/e1ab7ccfaad6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4eb/5054403/e1ab7ccfaad6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4eb/5054403/e1ab7ccfaad6/gr1.jpg

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J Biomed Inform. 2009 Feb;42(1):140-9. doi: 10.1016/j.jbi.2008.05.006. Epub 2008 May 23.
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Prolyl cis-trans isomerization as a molecular timer.脯氨酰顺反异构化作为一种分子计时器。
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COPS--cis/trans peptide bond conformation prediction of amino acids on the basis of secondary structure information.COPS——基于二级结构信息预测氨基酸的顺式/反式肽键构象
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Support vector machines for prediction of peptidyl prolyl cis/trans isomerization.用于预测肽基脯氨酰顺反异构化的支持向量机
J Pept Res. 2004 Jan;63(1):23-8. doi: 10.1046/j.1399-3011.2004.00100.x.
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RVP-net: online prediction of real valued accessible surface area of proteins from single sequences.RVP-net:从单序列在线预测蛋白质的实值可及表面积
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