Department of Anesthesia, University Hospital Basel, Basel, Switzerland.
J Cardiothorac Vasc Anesth. 2010 Apr;24(2):270-4. doi: 10.1053/j.jvca.2009.09.010. Epub 2009 Nov 27.
Myocardial performance index, the sum of the 2 isovolumic times divided by the ejection time, contains information on global systolic and diastolic function. This study was performed to determine the feasibility of right ventricular myocardial performance index measurements if measured by transesophageal echocardiography in patients under general anesthesia and positive-pressure ventilation.
A prospective cohort study.
A tertiary care university hospital.
Twenty patients undergoing elective coronary artery bypass graft surgery.
None.
The feasibility of the right ventricular myocardial performance index measurements was assessed in awake patients by using transthoracic echocardiography and reassessed in the same patients under general anesthesia and positive-pressure ventilation using transesophageal echocardiography. The time from the cessation to the onset of 2 consecutive right ventricular inflows was measured as time A; the time from the onset to the cessation of right ventricular ejection was measured as time B. Myocardial performance index was calculated as follows: (time A-time B)/time B. A first reader independently measured all recordings twice to assess intrareader variability and a second reader once to assess interreader variability. Variability (%) was calculated as the mean absolute difference between 2 readings divided by their mean. The myocardial performance index could be measured for all patients. The point estimates of inter- and intraobserver variability of the right ventricular myocardial performance index measurements were 4.3% to 5% in awake patients and 17.8% to 19.6% in anesthetized patients.
This finding questions the use of right ventricular myocardial performance index measurements in anesthetized patients under positive-pressure ventilation.
心肌做功指数是等容收缩时间和等容舒张时间之和与射血时间的比值,包含了整体收缩和舒张功能的信息。本研究旨在确定在全麻正压通气下经食管超声心动图测量右心室心肌做功指数的可行性。
前瞻性队列研究。
三级护理大学医院。
20 例行择期冠状动脉旁路移植术的患者。
无。
通过经胸超声心动图评估清醒患者右心室心肌做功指数测量的可行性,然后在同一患者全麻正压通气下通过经食管超声心动图重新评估。测量连续 2 个右心室流入的起始到终止的时间作为时间 A;测量右心室射血的起始到终止的时间作为时间 B。右心室心肌做功指数的计算方法如下:(时间 A-时间 B)/时间 B。一位初读者独立测量所有记录两次,以评估内部读者的可变性,另一位读者测量一次,以评估外部读者的可变性。可变性(%)的计算方法为两次读数的平均绝对差值除以平均值。所有患者均能测量右心室心肌做功指数。在清醒患者中,右心室心肌做功指数测量的观察者内和观察者间变异的点估计值为 4.3%至 5%,在麻醉患者中为 17.8%至 19.6%。
这一发现质疑了在正压通气下麻醉患者中使用右心室心肌做功指数测量的可行性。