Kolling Institute, University of Sydney, St Leonards, Sydney 2065, Australia.
Best Pract Res Clin Rheumatol. 2009 Dec;23(6):769-79. doi: 10.1016/j.berh.2009.09.006.
Secondary osteoporosis is a common cause of osteoporosis, and there are many medical conditions associated with osteoporosis. Many of these present well before osteoporosis develops, and knowledge of these pre-existing conditions may influence the decision about whether to test and/or treat for osteoporosis. Men and premenopausal women with unexplained osteoporosis or a history of fragility fracture should undergo investigation for secondary osteoporosis. Postmenopausal women with risk factors for secondary osteoporosis should also be carefully evaluated. Beyond the well-recognised association with glucocorticoids, an increasing list of drugs has been implicated in causing bone loss and fractures. With appropriate consideration of secondary causes and relevant investigations, many of these conditions are preventable with newer therapies.
继发性骨质疏松症是骨质疏松症的常见病因，有许多与骨质疏松症相关的医学病症。其中许多病症在骨质疏松症发生之前就已经表现明显，了解这些先前存在的病症可能会影响是否进行骨质疏松症检测和/或治疗的决策。原因不明的骨质疏松症或脆性骨折史的男性和绝经前妇女应进行继发性骨质疏松症的检查。有继发性骨质疏松症风险因素的绝经后妇女也应仔细评估。除了与糖皮质激素的明确关联外，越来越多的药物也与骨丢失和骨折有关。通过适当考虑继发性原因和相关检查，许多这些病症都可以通过新的治疗方法预防。
