Hosomi Masahiro, Yoneda Suguru, Madono Keigo, Tanigawa Go, Yazawa Koji, Yamaguchi Seiji
The Department of Urology, Osaka General Medical Center, Japan.
Hinyokika Kiyo. 2009 Nov;55(11):665-9.
A retrospective clinicopathological study of 82 patients with invasive urothelial carcinoma treated with radical cystectomy was performed. There were 62 men and 20 women, median age at operation was 68-years-old and the 5-year overall cancer-specific survival rate was 82.5%. Univariate analyses demonstrated that female patients had poor prognosis, and that lymphovascular invasion was a predictor of recurrence. Multivariate Cox regression analyses including age, grade, and vascular invasion, showed that vascular invasion was an independent predictor of recurrence (HR4.46, P=0.008).
对82例行根治性膀胱切除术的浸润性尿路上皮癌患者进行了回顾性临床病理研究。其中男性62例，女性20例，手术时的中位年龄为68岁，5年总体癌症特异性生存率为82.5%。单因素分析表明，女性患者预后较差，且淋巴管浸润是复发的预测指标。包括年龄、分级和血管浸润在内的多因素Cox回归分析显示，血管浸润是复发的独立预测指标（HR4.46，P=0.008）。
