伴有异常自身免疫谱的毛发红糠疹：两例病例报告
Pityriasis rubra pilaris presenting with an abnormal autoimmune profile: two case reports.
作者信息
Gregoriou Stamatis, Chiolou Zoe, Stefanaki Christina, Zakopoulou Niki, Rigopoulos Dimitrios, Kontochristopoulos George
机构信息
University of Athens Medical School, Department of Dermatology, Athens, Greece.
出版信息
J Med Case Rep. 2009 Nov 13;3:123. doi: 10.1186/1752-1947-3-123.
INTRODUCTION
Pityriasis rubra pilaris is an uncommon inflammatory and hyperproliferative dermatosis of juvenile or adult onset. The etiology of the disease is still unknown.
CASE PRESENTATION
We present the cases of two Caucasian men aged 53 and 48 who presented with pityriasis rubra pillaris type 1; both patients also exhibited an abnormal immunological profile.
CONCLUSION
Pityriasis rubra pillaris is currently classified as a keratinization disorder. The abnormal immunological profile reported in our patients along with the comorbidity of pityriasis rubra pilaris with autoimmune disorders reported in the literature poses the question of a possible pathogenetic role for the immune response in this disorder.
引言
毛发红糠疹是一种不常见的炎症性和增殖性皮肤病，可发生于青少年或成人。该病病因尚不清楚。
病例报告
我们报告了两名分别为53岁和48岁的白种男性毛发红糠疹1型病例；两名患者均表现出异常的免疫特征。
结论
毛发红糠疹目前被归类为一种角化障碍性疾病。我们患者中报告的异常免疫特征以及文献中报道的毛发红糠疹与自身免疫性疾病的共病现象，引发了免疫反应在该疾病中可能的致病作用这一问题。
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