Kaluarachchi Athula, Marasinghe Jeevan P, Batcha Thuwan M, Agunawela Preethika
Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Colombo, Colombo 00800, Sri Lanka.
Obstet Gynecol Int. 2009;2009:492386. doi: 10.1155/2009/492386. Epub 2009 Feb 25.
We report a case of luteinizing thecoma in a 58-year-old postmenopausal woman who presented with progressive androgenic features and hypertension of one year duration. She did not notice a significant change in her body weight or appetite. Her total serum testosterone level was 4.5 ng/mL. Ultrasound scan revealed a normal-sized uterus and a right-sided solid ovarian mass of 5 cm x 5 cm. Left ovary was normal. She had a total abdominal hysterectomy, bilateral salpingo-oophorectomy, and an omentectomy performed. Histological examination confirmed the diagnosis of luteinized thecoma. This case illustrates the necessity to consider the rare possibility of luteinized ovarian thecoma as a cause for virilization in a menopausal woman.
我们报告一例58岁绝经后女性的黄素化卵泡膜细胞瘤,该患者出现进行性雄激素化特征及持续一年的高血压。她未注意到体重或食欲有明显变化。其血清总睾酮水平为4.5 ng/mL。超声扫描显示子宫大小正常,右侧卵巢有一个5 cm×5 cm的实性肿块。左侧卵巢正常。她接受了全腹子宫切除术、双侧输卵管卵巢切除术及大网膜切除术。组织学检查确诊为黄素化卵泡膜细胞瘤。该病例表明,对于绝经后女性出现男性化表现,有必要考虑黄素化卵巢卵泡膜细胞瘤这种罕见病因的可能性。