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一名绝经后女性出现男性化表现的卵巢卵泡膜细胞瘤。

Luteinized ovarian thecoma in a postmenopausal women presenting with virilization.

作者信息

Kaluarachchi Athula, Marasinghe Jeevan P, Batcha Thuwan M, Agunawela Preethika

机构信息

Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Colombo, Colombo 00800, Sri Lanka.

出版信息

Obstet Gynecol Int. 2009;2009:492386. doi: 10.1155/2009/492386. Epub 2009 Feb 25.

DOI:10.1155/2009/492386
PMID:19946643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2778823/
Abstract

We report a case of luteinizing thecoma in a 58-year-old postmenopausal woman who presented with progressive androgenic features and hypertension of one year duration. She did not notice a significant change in her body weight or appetite. Her total serum testosterone level was 4.5 ng/mL. Ultrasound scan revealed a normal-sized uterus and a right-sided solid ovarian mass of 5 cm x 5 cm. Left ovary was normal. She had a total abdominal hysterectomy, bilateral salpingo-oophorectomy, and an omentectomy performed. Histological examination confirmed the diagnosis of luteinized thecoma. This case illustrates the necessity to consider the rare possibility of luteinized ovarian thecoma as a cause for virilization in a menopausal woman.

摘要

我们报告一例58岁绝经后女性的黄素化卵泡膜细胞瘤,该患者出现进行性雄激素化特征及持续一年的高血压。她未注意到体重或食欲有明显变化。其血清总睾酮水平为4.5 ng/mL。超声扫描显示子宫大小正常,右侧卵巢有一个5 cm×5 cm的实性肿块。左侧卵巢正常。她接受了全腹子宫切除术、双侧输卵管卵巢切除术及大网膜切除术。组织学检查确诊为黄素化卵泡膜细胞瘤。该病例表明,对于绝经后女性出现男性化表现,有必要考虑黄素化卵巢卵泡膜细胞瘤这种罕见病因的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a92/2778823/9e49a2a5a927/OGI2009-492386.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a92/2778823/9e49a2a5a927/OGI2009-492386.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a92/2778823/9e49a2a5a927/OGI2009-492386.001.jpg

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本文引用的文献

1
Ovarian thecoma with androgenic manifestations in a postmenopausal woman.一名绝经后女性出现具有雄激素表现的卵巢卵泡膜细胞瘤。
Gynecol Endocrinol. 2006 Jul;22(7):405-8. doi: 10.1080/09513590600842539.
2
Ovarian steroid cell tumor and a contralateral ovarian thecoma in a postmenopausal woman with severe hyperandrogenism.一名患有严重雄激素过多症的绝经后女性,其一侧卵巢存在类固醇细胞瘤,对侧卵巢存在卵泡膜细胞瘤。
Gynecol Endocrinol. 2002 Jun;16(3):213-6.
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Arch Gynecol Obstet. 2000 Jul;264(1):42-4. doi: 10.1007/pl00007485.
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